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Research article:

Adaptation and validation of the Charlson Index for Read/OXMIS coded databases

Reference:

Nada F Khan, Rafael Perera, Stephen Harper, Peter W Rose(2010) Adaptation and validation of the Charlson Index for Read/OXMIS coded databases. BMC Family Practice, doi: 10.1186/1471-2296-11-1

Link to fulltext article
Abstract
Background The Charlson comorbidity index is widely used in ICD-9 administrative data, however, there is no translation for Read/OXMIS coded data despite increasing use of the General Practice Research Database (GPRD). Our main objective was to translate the Charlson index for use with Read/OXMIS coded data such as the GPRD and test its association with mortality. We also aimed to provide a version of the comorbidity index for other researchers using similar datasets. Methods Two clinicians translated the Charlson index into Read/OXMIS codes. We tested the association between comorbidity score and increased mortality in 146 441 patients from the GPRD using proportional hazards models. Results This Read/OXMIS translation of the Charlson index contains 3156 codes. Our validation showed a strong positive association between Charlson score and age. Cox proportional models show a positive increasing association with mortality and Charlson score. The discrimination of the logistic regression model for mortality was good (AUC = 0.853). Conclusion We have translated a commonly used comorbidity index into Read/OXMIS for use in UK primary care databases. The translated index showed a good discrimination in our study population. This is the first study to develop a co-morbidity index for use with the Read/OXMIS coding system and the GPRD. A copy of the co-morbidity index is provided for other researchers using similar databases.
Author for correspondence
Nada F Khan
Email for correspondence
nada.khan@dphpc.ox.ac.uk

Code list: res27: Congestive heart disease

40 codes in list

Code Coding system Description Entity type List name Charlson score weight
14A6.00 Read/OXMIS H/O: heart failure diagnostic res27: Congestive heart disease 1
14AM.00 Read/OXMIS H/O: Heart failure in last year diagnostic res27: Congestive heart disease 1
1O1..00 Read/OXMIS Heart failure confirmed diagnostic res27: Congestive heart disease 1
402 C Read/OXMIS HYPERTENSION CONGESTIVE HEART FAILURE diagnostic res27: Congestive heart disease 1
425 CC Read/OXMIS CONGESTIVE CARDIOMYOPATHY diagnostic res27: Congestive heart disease 1
4270 Read/OXMIS CONGESTIVE HEART FAILURE diagnostic res27: Congestive heart disease 1
4270C Read/OXMIS CONGESTIVE CARDIAC FAILURE diagnostic res27: Congestive heart disease 1
4270CC Read/OXMIS CONGESTIVE HEART FAILURE COMPENSATED diagnostic res27: Congestive heart disease 1
4270D Read/OXMIS CONGESTIVE HEART FAILURE DECOMPENSATED diagnostic res27: Congestive heart disease 1
4270R Read/OXMIS HEART FAILURE RIGHT-SIDED diagnostic res27: Congestive heart disease 1
4271 Read/OXMIS LVF (LEFT VENTRICULAR FAILURE) diagnostic res27: Congestive heart disease 1
4271A Read/OXMIS LEFT VENTRICULAR FAILURE ACUTE diagnostic res27: Congestive heart disease 1
4271B Read/OXMIS CARDIAC ASTHMA diagnostic res27: Congestive heart disease 1
4271H Read/OXMIS HEART FAILURE LEFT-SIDED diagnostic res27: Congestive heart disease 1
662W.00 Read/OXMIS Heart failure annual review diagnostic res27: Congestive heart disease 1
7824AC Read/OXMIS HEART FAILURE ACUTE diagnostic res27: Congestive heart disease 1
7824BW Read/OXMIS WEAK HEART diagnostic res27: Congestive heart disease 1
7824FH Read/OXMIS HEART FAILURE diagnostic res27: Congestive heart disease 1
7824FM Read/OXMIS MYOCARDIAL FAILURE diagnostic res27: Congestive heart disease 1
8B29.00 Read/OXMIS Cardiac failure therapy diagnostic res27: Congestive heart disease 1
8CL3.00 Read/OXMIS Heart failure care plan discussed with patient diagnostic res27: Congestive heart disease 1
8H2S.00 Read/OXMIS Admit heart failure emergency diagnostic res27: Congestive heart disease 1
G232.00 Read/OXMIS Hypertensive heart&renal dis wth (congestive) heart failure diagnostic res27: Congestive heart disease 1
G554000 Read/OXMIS Congestive cardiomyopathy diagnostic res27: Congestive heart disease 1
G58..00 Read/OXMIS Heart failure diagnostic res27: Congestive heart disease 1
G580.00 Read/OXMIS Congestive heart failure diagnostic res27: Congestive heart disease 1
G580000 Read/OXMIS Acute congestive heart failure diagnostic res27: Congestive heart disease 1
G580100 Read/OXMIS Chronic congestive heart failure diagnostic res27: Congestive heart disease 1
G580.11 Read/OXMIS Congestive cardiac failure diagnostic res27: Congestive heart disease 1
G580.12 Read/OXMIS Right heart failure diagnostic res27: Congestive heart disease 1
G580200 Read/OXMIS Decompensated cardiac failure diagnostic res27: Congestive heart disease 1
G580300 Read/OXMIS Compensated cardiac failure diagnostic res27: Congestive heart disease 1
G581.00 Read/OXMIS Left ventricular failure diagnostic res27: Congestive heart disease 1
G581000 Read/OXMIS Acute left ventricular failure diagnostic res27: Congestive heart disease 1
G58..11 Read/OXMIS Cardiac failure diagnostic res27: Congestive heart disease 1
G582.00 Read/OXMIS Acute heart failure diagnostic res27: Congestive heart disease 1
G58z.00 Read/OXMIS Heart failure NOS diagnostic res27: Congestive heart disease 1
G58z.11 Read/OXMIS Weak heart diagnostic res27: Congestive heart disease 1
G58z.12 Read/OXMIS Cardiac failure NOS diagnostic res27: Congestive heart disease 1
SP11111 Read/OXMIS Heart failure as a complication of care diagnostic res27: Congestive heart disease 1

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