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Research article:
Adaptation and validation of the Charlson Index for Read/OXMIS coded databases
Reference:
Nada F Khan, Rafael Perera, Stephen Harper, Peter W Rose(2010) Adaptation and validation of the Charlson Index for Read/OXMIS coded databases. BMC Family Practice, doi: 10.1186/1471-2296-11-1
- Link to fulltext article
- Abstract
- Background The Charlson comorbidity index is widely used in ICD-9 administrative data, however, there is no translation for Read/OXMIS coded data despite increasing use of the General Practice Research Database (GPRD). Our main objective was to translate the Charlson index for use with Read/OXMIS coded data such as the GPRD and test its association with mortality. We also aimed to provide a version of the comorbidity index for other researchers using similar datasets. Methods Two clinicians translated the Charlson index into Read/OXMIS codes. We tested the association between comorbidity score and increased mortality in 146 441 patients from the GPRD using proportional hazards models. Results This Read/OXMIS translation of the Charlson index contains 3156 codes. Our validation showed a strong positive association between Charlson score and age. Cox proportional models show a positive increasing association with mortality and Charlson score. The discrimination of the logistic regression model for mortality was good (AUC = 0.853). Conclusion We have translated a commonly used comorbidity index into Read/OXMIS for use in UK primary care databases. The translated index showed a good discrimination in our study population. This is the first study to develop a co-morbidity index for use with the Read/OXMIS coding system and the GPRD. A copy of the co-morbidity index is provided for other researchers using similar databases.
- Author for correspondence
- Nada F Khan
- Email for correspondence
- nada.khan@dphpc.ox.ac.uk
Code list: res27: Hemiplegia
23 codes in list
| Code | Coding system | Description | Entity type | List name | Charlson score weight | ||
|---|---|---|---|---|---|---|---|
| 2833 | Read/OXMIS | O/E - hemiplegia | diagnostic | res27: Hemiplegia | 2 | ||
| 2835 | Read/OXMIS | O/E - paraplegia | diagnostic | res27: Hemiplegia | 2 | ||
| 343 PR | Read/OXMIS | SPASTIC PARAPLEGIA | diagnostic | res27: Hemiplegia | 2 | ||
| 344 B | Read/OXMIS | PARALYSIS HEMIPLEGIA | diagnostic | res27: Hemiplegia | 2 | ||
| 344 BF | Read/OXMIS | HEMIPLEGIA FLACCID | diagnostic | res27: Hemiplegia | 2 | ||
| 344 BL | Read/OXMIS | HEMIPLEGIA LEFT | diagnostic | res27: Hemiplegia | 2 | ||
| 344 BR | Read/OXMIS | HEMIPLEGIA RIGHT | diagnostic | res27: Hemiplegia | 2 | ||
| 344 G | Read/OXMIS | PARAPLEGIA | diagnostic | res27: Hemiplegia | 2 | ||
| 344 SH | Read/OXMIS | SPASTIC HEMIPLEGIA | diagnostic | res27: Hemiplegia | 2 | ||
| 4360HP | Read/OXMIS | HYPERTENSIVE HEMIPLEGIA | diagnostic | res27: Hemiplegia | 2 | ||
| 4380HP | Read/OXMIS | HEMIPLEGIA WITH HYPERTENSION | diagnostic | res27: Hemiplegia | 2 | ||
| F141.00 | Read/OXMIS | Hereditary spastic paraplegia | diagnostic | res27: Hemiplegia | 2 | ||
| F22..00 | Read/OXMIS | Hemiplegia | diagnostic | res27: Hemiplegia | 2 | ||
| F220.00 | Read/OXMIS | Flaccid hemiplegia | diagnostic | res27: Hemiplegia | 2 | ||
| F221.00 | Read/OXMIS | Spastic hemiplegia | diagnostic | res27: Hemiplegia | 2 | ||
| F222.00 | Read/OXMIS | Left hemiplegia | diagnostic | res27: Hemiplegia | 2 | ||
| F223.00 | Read/OXMIS | Right hemiplegia | diagnostic | res27: Hemiplegia | 2 | ||
| F22z.00 | Read/OXMIS | Hemiplegia NOS | diagnostic | res27: Hemiplegia | 2 | ||
| F230000 | Read/OXMIS | Congenital paraplegia | diagnostic | res27: Hemiplegia | 2 | ||
| F230.11 | Read/OXMIS | Paraplegia - congenital | diagnostic | res27: Hemiplegia | 2 | ||
| F241.00 | Read/OXMIS | Paraplegia | diagnostic | res27: Hemiplegia | 2 | ||
| F241000 | Read/OXMIS | Flaccid paraplegia | diagnostic | res27: Hemiplegia | 2 | ||
| F241100 | Read/OXMIS | Spastic paraplegia | diagnostic | res27: Hemiplegia | 2 |
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