ClinicalCodes.org
An online clinical codes repository to improve validity and reproducibility of medical database research
Research article:
Adaptation and validation of the Charlson Index for Read/OXMIS coded databases
Reference:
Nada F Khan, Rafael Perera, Stephen Harper, Peter W Rose(2010) Adaptation and validation of the Charlson Index for Read/OXMIS coded databases. BMC Family Practice, doi: 10.1186/1471-2296-11-1
- Link to fulltext article
- Abstract
- Background The Charlson comorbidity index is widely used in ICD-9 administrative data, however, there is no translation for Read/OXMIS coded data despite increasing use of the General Practice Research Database (GPRD). Our main objective was to translate the Charlson index for use with Read/OXMIS coded data such as the GPRD and test its association with mortality. We also aimed to provide a version of the comorbidity index for other researchers using similar datasets. Methods Two clinicians translated the Charlson index into Read/OXMIS codes. We tested the association between comorbidity score and increased mortality in 146 441 patients from the GPRD using proportional hazards models. Results This Read/OXMIS translation of the Charlson index contains 3156 codes. Our validation showed a strong positive association between Charlson score and age. Cox proportional models show a positive increasing association with mortality and Charlson score. The discrimination of the logistic regression model for mortality was good (AUC = 0.853). Conclusion We have translated a commonly used comorbidity index into Read/OXMIS for use in UK primary care databases. The translated index showed a good discrimination in our study population. This is the first study to develop a co-morbidity index for use with the Read/OXMIS coding system and the GPRD. A copy of the co-morbidity index is provided for other researchers using similar databases.
- Author for correspondence
- Nada F Khan
- Email for correspondence
- nada.khan@dphpc.ox.ac.uk
Code list: res27: Mod liver disease
21 codes in list
| Code | Coding system | Description | Entity type | List name | Charlson score weight | ||
|---|---|---|---|---|---|---|---|
| 5719PH | Read/OXMIS | PORTAL HYPERTENSION | diagnostic | res27: Mod liver disease | 3 | ||
| 573 B | Read/OXMIS | HEPATIC COMA | diagnostic | res27: Mod liver disease | 3 | ||
| 573 HR | Read/OXMIS | SYNDROME HEPATORENAL | diagnostic | res27: Mod liver disease | 3 | ||
| 760F300 | Read/OXMIS | Rigid oesophagoscopic injection sclerotherapy oesoph varices | diagnostic | res27: Mod liver disease | 3 | ||
| A704z00 | Read/OXMIS | Other specified viral hepatitis with hepatic coma NOS | diagnostic | res27: Mod liver disease | 3 | ||
| G850.00 | Read/OXMIS | Oesophageal varices with bleeding | diagnostic | res27: Mod liver disease | 3 | ||
| G851.00 | Read/OXMIS | Oesophageal varices without bleeding | diagnostic | res27: Mod liver disease | 3 | ||
| G85..11 | Read/OXMIS | Oesophageal varices | diagnostic | res27: Mod liver disease | 3 | ||
| G852.00 | Read/OXMIS | Oesophageal varices in diseases EC | diagnostic | res27: Mod liver disease | 3 | ||
| G852000 | Read/OXMIS | Oesophageal varices with bleeding in diseases EC | diagnostic | res27: Mod liver disease | 3 | ||
| G852100 | Read/OXMIS | Oesophageal varices without bleeding in diseases EC | diagnostic | res27: Mod liver disease | 3 | ||
| G852200 | Read/OXMIS | Oesophageal varices in cirrhosis of the liver | diagnostic | res27: Mod liver disease | 3 | ||
| G852300 | Read/OXMIS | Oesophageal varices in alcoholic cirrhosis of the liver | diagnostic | res27: Mod liver disease | 3 | ||
| G852z00 | Read/OXMIS | Oesophageal varices in diseases EC NOS | diagnostic | res27: Mod liver disease | 3 | ||
| G858.00 | Read/OXMIS | Oesophageal varices NOS | diagnostic | res27: Mod liver disease | 3 | ||
| Gyu9400 | Read/OXMIS | [X]Oesophageal varices in diseases classified elsewhere | diagnostic | res27: Mod liver disease | 3 | ||
| J622.00 | Read/OXMIS | Hepatic coma | diagnostic | res27: Mod liver disease | 3 | ||
| J623.00 | Read/OXMIS | Portal hypertension | diagnostic | res27: Mod liver disease | 3 | ||
| J624.00 | Read/OXMIS | Hepatorenal syndrome | diagnostic | res27: Mod liver disease | 3 | ||
| J62y.00 | Read/OXMIS | Other sequelae of chronic liver disease | diagnostic | res27: Mod liver disease | 3 | ||
| J62z.00 | Read/OXMIS | Liver abscess and chronic liver disease causing sequelae NOS | diagnostic | res27: Mod liver disease | 3 |
Please log in to leave a comment.
Code list links:
ClinicalCodes is a project at the University of Manchester Institute of Population Health
The ClinicalCodes project is funded by the National Institute for Health Research (NIHR) School for Primary Care Research (SPCR)