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Research article:
Adaptation and validation of the Charlson Index for Read/OXMIS coded databases
Reference:
Nada F Khan, Rafael Perera, Stephen Harper, Peter W Rose(2010) Adaptation and validation of the Charlson Index for Read/OXMIS coded databases. BMC Family Practice, doi: 10.1186/1471-2296-11-1
- Link to fulltext article
- Abstract
- Background The Charlson comorbidity index is widely used in ICD-9 administrative data, however, there is no translation for Read/OXMIS coded data despite increasing use of the General Practice Research Database (GPRD). Our main objective was to translate the Charlson index for use with Read/OXMIS coded data such as the GPRD and test its association with mortality. We also aimed to provide a version of the comorbidity index for other researchers using similar datasets. Methods Two clinicians translated the Charlson index into Read/OXMIS codes. We tested the association between comorbidity score and increased mortality in 146 441 patients from the GPRD using proportional hazards models. Results This Read/OXMIS translation of the Charlson index contains 3156 codes. Our validation showed a strong positive association between Charlson score and age. Cox proportional models show a positive increasing association with mortality and Charlson score. The discrimination of the logistic regression model for mortality was good (AUC = 0.853). Conclusion We have translated a commonly used comorbidity index into Read/OXMIS for use in UK primary care databases. The translated index showed a good discrimination in our study population. This is the first study to develop a co-morbidity index for use with the Read/OXMIS coding system and the GPRD. A copy of the co-morbidity index is provided for other researchers using similar databases.
- Author for correspondence
- Nada F Khan
- Email for correspondence
- nada.khan@dphpc.ox.ac.uk
Code list: res27: Peripheral vascular disease
62 codes in list
| Code | Coding system | Description | Entity type | List name | Charlson score weight | ||
|---|---|---|---|---|---|---|---|
| 14AE.00 | Read/OXMIS | H/O: aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 14NB.00 | Read/OXMIS | H/O: Peripheral vascular disease procedure | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 2I16.00 | Read/OXMIS | O/E - gangrene | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 4410N | Read/OXMIS | DISSECTION AORTA | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 4419 | Read/OXMIS | AORTIC ANEURYSM | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 4430G | Read/OXMIS | SYMMETRICAL GANGRENE EXTREMITIES | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 4439A | Read/OXMIS | INTERMITTENT CLAUDICATION | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 4439GD | Read/OXMIS | PVD (PERIPHERAL VASCULAR DISEASE) | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 4459CR | Read/OXMIS | ULCER WITH GANGRENE | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 4459FT | Read/OXMIS | GANGRENE FOOT | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 4459N | Read/OXMIS | GANGRENE | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 4459TE | Read/OXMIS | GANGRENE TOE | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 6075GM | Read/OXMIS | SCROTAL GANGRENE | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 7A11211 | Read/OXMIS | Y graft of abdominal Aortic aneurysm (emergency) | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 7A11311 | Read/OXMIS | Y graft abdominal Aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 7A13.11 | Read/OXMIS | Emergency repair of aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 7A13411 | Read/OXMIS | Tube graft abdominal Aortic aneurysm (emergency) | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 7A14.11 | Read/OXMIS | Aortic aneurysm repair | diagnostic | res27: Peripheral vascular disease | 1 | ||
| 7A14411 | Read/OXMIS | Tube graft of Abdominal aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| C107.12 | Read/OXMIS | Diabetes with gangrene | diagnostic | res27: Peripheral vascular disease | 1 | ||
| g71..00 | Read/OXMIS | Aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G71..00 | Read/OXMIS | Aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G710.00 | Read/OXMIS | Dissecting aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G711.00 | Read/OXMIS | Thoracic aortic aneurysm which has ruptured | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G711.11 | Read/OXMIS | Ruptured thoracic aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G712.00 | Read/OXMIS | Thoracic aortic aneurysm without mention of rupture | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G713.00 | Read/OXMIS | Abdominal aortic aneurysm which has ruptured | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G713000 | Read/OXMIS | Ruptured suprarenal aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G713.11 | Read/OXMIS | Ruptured abdominal aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G714.00 | Read/OXMIS | Abdominal aortic aneurysm without mention of rupture | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G714000 | Read/OXMIS | Juxtarenal aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G714100 | Read/OXMIS | Inflammatory abdominal aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G714.11 | Read/OXMIS | AAA - Abdominal aortic aneurysm without mention of rupture | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G715.00 | Read/OXMIS | Ruptured aortic aneurysm NOS | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G715000 | Read/OXMIS | Thoracoabdominal aortic aneurysm; ruptured | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G716.00 | Read/OXMIS | Aortic aneurysm without mention of rupture NOS | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G716000 | Read/OXMIS | Thoracoabdominal aortic aneurysm; without mention of rupture | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G718.00 | Read/OXMIS | Leaking abdominal aortic aneurysm | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G71z.00 | Read/OXMIS | Aortic aneurysm NOS | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G73..00 | Read/OXMIS | Other peripheral vascular disease | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G73..11 | Read/OXMIS | Peripheral ischaemic vascular disease | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G731100 | Read/OXMIS | Presenile gangrene | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G732.00 | Read/OXMIS | Peripheral gangrene | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G732000 | Read/OXMIS | Gangrene of toe | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G732100 | Read/OXMIS | Gangrene of foot | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G732200 | Read/OXMIS | Gangrene of finger | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G732300 | Read/OXMIS | Gangrene of thumb | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G732400 | Read/OXMIS | Gangrene of hand | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G73y.00 | Read/OXMIS | Other specified peripheral vascular disease | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G73yz00 | Read/OXMIS | Other specified peripheral vascular disease NOS | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G73z.00 | Read/OXMIS | Peripheral vascular disease NOS | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G73z000 | Read/OXMIS | Intermittent claudication | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G73z011 | Read/OXMIS | Claudication | diagnostic | res27: Peripheral vascular disease | 1 | ||
| G73zz00 | Read/OXMIS | Peripheral vascular disease NOS | diagnostic | res27: Peripheral vascular disease | 1 | ||
| Gyu7100 | Read/OXMIS | [X]Aortic aneurysm of unspecified site; ruptured | diagnostic | res27: Peripheral vascular disease | 1 | ||
| Gyu7200 | Read/OXMIS | [X]Aortic aneurysm of unspecified site; nonruptured | diagnostic | res27: Peripheral vascular disease | 1 | ||
| Gyu7400 | Read/OXMIS | [X]Other specified peripheral vascular diseases | diagnostic | res27: Peripheral vascular disease | 1 | ||
| R054.00 | Read/OXMIS | [D]Gangrene | diagnostic | res27: Peripheral vascular disease | 1 | ||
| R054000 | Read/OXMIS | [D]Gangrene; spreading cutaneous | diagnostic | res27: Peripheral vascular disease | 1 | ||
| R054200 | Read/OXMIS | [D]Gangrene of toe in diabetic | diagnostic | res27: Peripheral vascular disease | 1 | ||
| R054300 | Read/OXMIS | [D]Widespread diabetic foot gangrene | diagnostic | res27: Peripheral vascular disease | 1 | ||
| R054z00 | Read/OXMIS | [D]Gangrene NOS | diagnostic | res27: Peripheral vascular disease | 1 |
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