ClinicalCodes.org
An online clinical codes repository to improve validity and reproducibility of medical database research
Research article:
Adaptation and validation of the Charlson Index for Read/OXMIS coded databases
Reference:
Nada F Khan, Rafael Perera, Stephen Harper, Peter W Rose(2010) Adaptation and validation of the Charlson Index for Read/OXMIS coded databases. BMC Family Practice, doi: 10.1186/1471-2296-11-1
- Link to fulltext article
- Abstract
- Background The Charlson comorbidity index is widely used in ICD-9 administrative data, however, there is no translation for Read/OXMIS coded data despite increasing use of the General Practice Research Database (GPRD). Our main objective was to translate the Charlson index for use with Read/OXMIS coded data such as the GPRD and test its association with mortality. We also aimed to provide a version of the comorbidity index for other researchers using similar datasets. Methods Two clinicians translated the Charlson index into Read/OXMIS codes. We tested the association between comorbidity score and increased mortality in 146 441 patients from the GPRD using proportional hazards models. Results This Read/OXMIS translation of the Charlson index contains 3156 codes. Our validation showed a strong positive association between Charlson score and age. Cox proportional models show a positive increasing association with mortality and Charlson score. The discrimination of the logistic regression model for mortality was good (AUC = 0.853). Conclusion We have translated a commonly used comorbidity index into Read/OXMIS for use in UK primary care databases. The translated index showed a good discrimination in our study population. This is the first study to develop a co-morbidity index for use with the Read/OXMIS coding system and the GPRD. A copy of the co-morbidity index is provided for other researchers using similar databases.
- Author for correspondence
- Nada F Khan
- Email for correspondence
- nada.khan@dphpc.ox.ac.uk
Code list: res27: Rheumatological disease
102 codes in list
| Code | Coding system | Description | Entity type | List name | Charlson score weight | ||
|---|---|---|---|---|---|---|---|
| 2A42.00 | Read/OXMIS | SYSTEMIC LUPUS ERYTHEMATOSUS WITH RENAL | diagnostic | res27: Rheumatological disease | 1 | ||
| 6954 | Read/OXMIS | SYSTEMIC LUPUS ERYTHEMATOSUS | diagnostic | res27: Rheumatological disease | 1 | ||
| 7121 | Read/OXMIS | SYNDROME FELTY'S | diagnostic | res27: Rheumatological disease | 1 | ||
| 7123 | Read/OXMIS | RHEUMATOID ARTHRITIS | diagnostic | res27: Rheumatological disease | 1 | ||
| 7123CR | Read/OXMIS | RHEUMATOID ARTHRITIS INCREASED ACTIVITY | diagnostic | res27: Rheumatological disease | 1 | ||
| 7124A | Read/OXMIS | RHEUMATOID ARTHRITIS SPINE | diagnostic | res27: Rheumatological disease | 1 | ||
| 7149A | Read/OXMIS | RHEUMATIC ARTHRITIS | diagnostic | res27: Rheumatological disease | 1 | ||
| 715 MR | Read/OXMIS | MONOARTICULAR RHEUMATISM | diagnostic | res27: Rheumatological disease | 1 | ||
| 7161 | Read/OXMIS | POLYMYOSITIS | diagnostic | res27: Rheumatological disease | 1 | ||
| 7179FN | Read/OXMIS | RHEUMATISM NONARTICULAR | diagnostic | res27: Rheumatological disease | 1 | ||
| 7179G | Read/OXMIS | RHEUMATISM MUSCULAR | diagnostic | res27: Rheumatological disease | 1 | ||
| 7179GA | Read/OXMIS | RHEUMATISM MUSCULAR ARM | diagnostic | res27: Rheumatological disease | 1 | ||
| 7179GB | Read/OXMIS | RHEUMATISM NONARTICULAR SHOULDER | diagnostic | res27: Rheumatological disease | 1 | ||
| 7179PR | Read/OXMIS | POLYMYALGIA RHEUMATICA | diagnostic | res27: Rheumatological disease | 1 | ||
| 718 | Read/OXMIS | RHEUMATISM | diagnostic | res27: Rheumatological disease | 1 | ||
| 718 AH | Read/OXMIS | RHEUMATISM HANDS | diagnostic | res27: Rheumatological disease | 1 | ||
| 718 BH | Read/OXMIS | RHEUMATISM HANDS ACUTE | diagnostic | res27: Rheumatological disease | 1 | ||
| 7340A | Read/OXMIS | SCLERODERMA | diagnostic | res27: Rheumatological disease | 1 | ||
| 7340BA | Read/OXMIS | ACROSCLEROSIS | diagnostic | res27: Rheumatological disease | 1 | ||
| 7340BC | Read/OXMIS | SCLERODERMA ACROSCLEROTIC | diagnostic | res27: Rheumatological disease | 1 | ||
| 7340C | Read/OXMIS | SCLERODERMA DIFFUSE | diagnostic | res27: Rheumatological disease | 1 | ||
| 7340D | Read/OXMIS | SCLERODERMA GENERALIZED | diagnostic | res27: Rheumatological disease | 1 | ||
| 7341 | Read/OXMIS | LUPUS ERYTHEMATOSUS DISSEMINATED | diagnostic | res27: Rheumatological disease | 1 | ||
| 7341AA | Read/OXMIS | LUPUS ERYTHEMATOSUS SYSTEMIC | diagnostic | res27: Rheumatological disease | 1 | ||
| 7341AC | Read/OXMIS | ACUTE SYSTEMIC LUPUS ERYTHEMATOSUS | diagnostic | res27: Rheumatological disease | 1 | ||
| 7341AD | Read/OXMIS | LUPUS ERYTHEMATOSUS ACUTE | diagnostic | res27: Rheumatological disease | 1 | ||
| 7341CL | Read/OXMIS | LIBMAN- SACKS DISEASE | diagnostic | res27: Rheumatological disease | 1 | ||
| F371200 | Read/OXMIS | Polyneuropathy in rheumatoid arthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| F396100 | Read/OXMIS | Myopathy due to disseminated lupus erythematosus | diagnostic | res27: Rheumatological disease | 1 | ||
| F396400 | Read/OXMIS | Myopathy due to rheumatoid arthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| F396600 | Read/OXMIS | Myopathy due to scleroderma | diagnostic | res27: Rheumatological disease | 1 | ||
| G5yA.00 | Read/OXMIS | Rheumatoid carditis | diagnostic | res27: Rheumatological disease | 1 | ||
| H570.00 | Read/OXMIS | Rheumatoid lung | diagnostic | res27: Rheumatological disease | 1 | ||
| H572.00 | Read/OXMIS | Lung disease with systemic sclerosis | diagnostic | res27: Rheumatological disease | 1 | ||
| H57y100 | Read/OXMIS | Lung disease with polymyositis | diagnostic | res27: Rheumatological disease | 1 | ||
| H57y400 | Read/OXMIS | Lung disease with systemic lupus erythematosus | diagnostic | res27: Rheumatological disease | 1 | ||
| K01x400 | Read/OXMIS | Nephrotic syndrome in systemic lupus erythematosus | diagnostic | res27: Rheumatological disease | 1 | ||
| K01x411 | Read/OXMIS | Lupus nephritis | diagnostic | res27: Rheumatological disease | 1 | ||
| L 151E | Read/OXMIS | SERO NEGATIVE RHEUMATOID ARTHRITIS | diagnostic | res27: Rheumatological disease | 1 | ||
| L 151F | Read/OXMIS | SERO POSITIVE RHEUMATOID ARTHRITIS | diagnostic | res27: Rheumatological disease | 1 | ||
| N000.00 | Read/OXMIS | Systemic lupus erythematosus | diagnostic | res27: Rheumatological disease | 1 | ||
| N000000 | Read/OXMIS | Disseminated lupus erythematosus | diagnostic | res27: Rheumatological disease | 1 | ||
| N000100 | Read/OXMIS | Libman-Sacks disease | diagnostic | res27: Rheumatological disease | 1 | ||
| N000200 | Read/OXMIS | Drug-induced systemic lupus erythematosus | diagnostic | res27: Rheumatological disease | 1 | ||
| N000300 | Read/OXMIS | Systemic lupus erythematosus with organ or sys involv | diagnostic | res27: Rheumatological disease | 1 | ||
| N000400 | Read/OXMIS | Systemic lupus erythematosus with pericarditis | diagnostic | res27: Rheumatological disease | 1 | ||
| N000z00 | Read/OXMIS | Systemic lupus erythematosus NOS | diagnostic | res27: Rheumatological disease | 1 | ||
| N001.00 | Read/OXMIS | Scleroderma | diagnostic | res27: Rheumatological disease | 1 | ||
| N001000 | Read/OXMIS | Progressive systemic sclerosis | diagnostic | res27: Rheumatological disease | 1 | ||
| N001.11 | Read/OXMIS | Acrosclerosis | diagnostic | res27: Rheumatological disease | 1 | ||
| N001.12 | Read/OXMIS | Systemic sclerosis | diagnostic | res27: Rheumatological disease | 1 | ||
| N001200 | Read/OXMIS | Systemic sclerosis induced by drugs and chemicals | diagnostic | res27: Rheumatological disease | 1 | ||
| N004.00 | Read/OXMIS | Polymyositis | diagnostic | res27: Rheumatological disease | 1 | ||
| N04..00 | Read/OXMIS | Rheumatoid arthritis and other inflammatory polyarthropathy | diagnostic | res27: Rheumatological disease | 1 | ||
| N040.00 | Read/OXMIS | Rheumatoid arthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| N040200 | Read/OXMIS | Rheumatoid arthritis of shoulder | diagnostic | res27: Rheumatological disease | 1 | ||
| N040300 | Read/OXMIS | Rheumatoid arthritis of sternoclavicular joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040400 | Read/OXMIS | Rheumatoid arthritis of acromioclavicular joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040500 | Read/OXMIS | Rheumatoid arthritis of elbow | diagnostic | res27: Rheumatological disease | 1 | ||
| N040600 | Read/OXMIS | Rheumatoid arthritis of distal radio-ulnar joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040700 | Read/OXMIS | Rheumatoid arthritis of wrist | diagnostic | res27: Rheumatological disease | 1 | ||
| N040800 | Read/OXMIS | Rheumatoid arthritis of MCP joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040900 | Read/OXMIS | Rheumatoid arthritis of PIP joint of finger | diagnostic | res27: Rheumatological disease | 1 | ||
| N040A00 | Read/OXMIS | Rheumatoid arthritis of DIP joint of finger | diagnostic | res27: Rheumatological disease | 1 | ||
| N040B00 | Read/OXMIS | Rheumatoid arthritis of hip | diagnostic | res27: Rheumatological disease | 1 | ||
| N040C00 | Read/OXMIS | Rheumatoid arthritis of sacro-iliac joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040D00 | Read/OXMIS | Rheumatoid arthritis of knee | diagnostic | res27: Rheumatological disease | 1 | ||
| N040E00 | Read/OXMIS | Rheumatoid arthritis of tibio-fibular joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040F00 | Read/OXMIS | Rheumatoid arthritis of ankle | diagnostic | res27: Rheumatological disease | 1 | ||
| N040G00 | Read/OXMIS | Rheumatoid arthritis of subtalar joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040H00 | Read/OXMIS | Rheumatoid arthritis of talonavicular joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040J00 | Read/OXMIS | Rheumatoid arthritis of other tarsal joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040K00 | Read/OXMIS | Rheumatoid arthritis of 1st MTP joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040L00 | Read/OXMIS | Rheumatoid arthritis of lesser MTP joint | diagnostic | res27: Rheumatological disease | 1 | ||
| N040M00 | Read/OXMIS | Rheumatoid arthritis of IP joint of toe | diagnostic | res27: Rheumatological disease | 1 | ||
| N040P00 | Read/OXMIS | Seronegative rheumatoid arthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| N040T00 | Read/OXMIS | Flare of rheumatoid arthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| N041.00 | Read/OXMIS | Felty's syndrome | diagnostic | res27: Rheumatological disease | 1 | ||
| N042100 | Read/OXMIS | Rheumatoid lung disease | diagnostic | res27: Rheumatological disease | 1 | ||
| N047.00 | Read/OXMIS | Seropositive errosive rheumatoid arthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| N04X.00 | Read/OXMIS | Seropositive rheumatoid arthritis; unspecified | diagnostic | res27: Rheumatological disease | 1 | ||
| N04y000 | Read/OXMIS | Rheumatoid lung | diagnostic | res27: Rheumatological disease | 1 | ||
| N04y011 | Read/OXMIS | Caplan's syndrome | diagnostic | res27: Rheumatological disease | 1 | ||
| N04y012 | Read/OXMIS | Fibrosing alveolitis associated with rheumatoid arthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| N04y111 | Read/OXMIS | Sero negative polyarthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| N060.11 | Read/OXMIS | Endemic polyarthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| N20..00 | Read/OXMIS | Polymyalgia rheumatica | diagnostic | res27: Rheumatological disease | 1 | ||
| N200.00 | Read/OXMIS | Giant cell arteritis with polymyalgia rheumatica | diagnostic | res27: Rheumatological disease | 1 | ||
| N231400 | Read/OXMIS | Polymyositis ossificans | diagnostic | res27: Rheumatological disease | 1 | ||
| N240.00 | Read/OXMIS | Rheumatism and fibrositis unspecified | diagnostic | res27: Rheumatological disease | 1 | ||
| N240000 | Read/OXMIS | Rheumatism unspecified | diagnostic | res27: Rheumatological disease | 1 | ||
| N240200 | Read/OXMIS | Muscular rheumatism | diagnostic | res27: Rheumatological disease | 1 | ||
| N240700 | Read/OXMIS | Hand rheumatism | diagnostic | res27: Rheumatological disease | 1 | ||
| N240z00 | Read/OXMIS | Rheumatism or fibrositis NOS | diagnostic | res27: Rheumatological disease | 1 | ||
| N2y..00 | Read/OXMIS | Other specified nonarticular rheumatism | diagnostic | res27: Rheumatological disease | 1 | ||
| N2z..00 | Read/OXMIS | Nonarticular rheumatism NOS | diagnostic | res27: Rheumatological disease | 1 | ||
| Nyu1000 | Read/OXMIS | [X]Rheumatoid arthritis?????? organs or systems | diagnostic | res27: Rheumatological disease | 1 | ||
| Nyu1100 | Read/OXMIS | [X]Other seropositive rheumatoid arthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| Nyu1200 | Read/OXMIS | [X]Other specified rheumatoid arthritis | diagnostic | res27: Rheumatological disease | 1 | ||
| Nyu1G00 | Read/OXMIS | [X]Seropositive rheumatoid arthritis; unspecified | diagnostic | res27: Rheumatological disease | 1 | ||
| Nyu4300 | Read/OXMIS | [X]Other forms of systemic lupus erythematosus | diagnostic | res27: Rheumatological disease | 1 | ||
| Nyu4500 | Read/OXMIS | [X]Other forms of systemic sclerosis | diagnostic | res27: Rheumatological disease | 1 |
Please log in to leave a comment.
Code list links:
ClinicalCodes is a project at the University of Manchester Institute of Population Health
The ClinicalCodes project is funded by the National Institute for Health Research (NIHR) School for Primary Care Research (SPCR)