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Research article:

Clinical management following self-harm in a UK-wide primary care cohort

Reference:

Matthew J Carr, Darren M Ashcroft, Evan Kontopantelis, David While, Yvonne Awenat, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb(2016) Clinical management following self-harm in a UK-wide primary care cohort. Journal of Affective Disorders, doi:

Link to article
Abstract
Background: Little is known about the clinical management of patients in primary care following self-harm. Methods: A descriptive cohort study using data from 684 UK general practices that contributed to the Clinical Practice Research Datalink (CPRD) during 2001-2013. We identified 49,970 patients with a self-harm episode, 41,500 of whom had one complete year of follow-up. Results: Among those with complete follow-up, 26,065 (62.8%, 62.3-63.3) were prescribed psychotropic medication and 6,318 (15.2%, 14.9-15.6) were referred to mental health services; 4,105 (9.9%, CI 9.6-10.2) were medicated without an antecedent psychiatric diagnosis or referral, and 4,506 (10.9%, CI 10.6-11.2) had a diagnosis but were not subsequently medicated or referred. Patients registered at practices in the most deprived localities were 27.1% (CI 21.5-32.2) less likely to be referred than those in the least deprived. Despite a specifically flagged NICE ‘Do not do’ recommendation in 2011 against prescribing tricyclic antidepressants following self-harm because of their potentially lethal toxicity in overdose, 8.8% (CI 7.8-9.8) of individuals were issued a prescription in the subsequent year. The percentage prescribed Citalopram, an SSRI antidepressant with higher toxicity in overdose, fell sharply during 2012/2013 in the aftermath of a Medicines and Healthcare products Regulatory Agency (MHRA) safety alert issued in 2011. Conclusions: A relatively small percentage of these vulnerable patients are referred to mental health services, and reduced likelihood of referral in more deprived localities reflects a marked health inequality. National clinical guidelines have not yet been effective in reducing rates of tricyclic antidepressant prescribing for this high-risk group.
Author for correspondence
Matthew J Carr
Email for correspondence
matthew.carr@manchester.ac.uk

Code list: res36: Bipolar disorder

111 codes in list

Code Coding system Description Entity type List name
146D.00 Read H/O: manic depressive disorder diagnostic res36: Bipolar disorder
1S42.00 Read Manic mood diagnostic res36: Bipolar disorder
6657.00 Read On lithium diagnostic res36: Bipolar disorder
6657.11 Read Lithium monitoring diagnostic res36: Bipolar disorder
6657.12 Read Started lithium diagnostic res36: Bipolar disorder
E11..00 Read Affective psychoses diagnostic res36: Bipolar disorder
E110.00 Read Manic disorder, single episode diagnostic res36: Bipolar disorder
E110000 Read Single manic episode, unspecified diagnostic res36: Bipolar disorder
E110100 Read Single manic episode, mild diagnostic res36: Bipolar disorder
E110.11 Read Hypomanic psychoses diagnostic res36: Bipolar disorder
E110200 Read Single manic episode, moderate diagnostic res36: Bipolar disorder
E110300 Read Single manic episode, severe without mention of psychosis diagnostic res36: Bipolar disorder
E110400 Read Single manic episode, severe, with psychosis diagnostic res36: Bipolar disorder
E110600 Read Single manic episode in full remission diagnostic res36: Bipolar disorder
E110z00 Read Manic disorder, single episode NOS diagnostic res36: Bipolar disorder
E111.00 Read Recurrent manic episodes diagnostic res36: Bipolar disorder
E111000 Read Recurrent manic episodes, unspecified diagnostic res36: Bipolar disorder
E11..11 Read Bipolar psychoses diagnostic res36: Bipolar disorder
E111100 Read Recurrent manic episodes, mild diagnostic res36: Bipolar disorder
E111200 Read Recurrent manic episodes, moderate diagnostic res36: Bipolar disorder
E11..13 Read Manic psychoses diagnostic res36: Bipolar disorder
E111300 Read Recurrent manic episodes, severe without mention psychosis diagnostic res36: Bipolar disorder
E111400 Read Recurrent manic episodes, severe, with psychosis diagnostic res36: Bipolar disorder
E111500 Read Recurrent manic episodes, partial or unspecified remission diagnostic res36: Bipolar disorder
E111600 Read Recurrent manic episodes, in full remission diagnostic res36: Bipolar disorder
E111z00 Read Recurrent manic episode NOS diagnostic res36: Bipolar disorder
E114.00 Read Bipolar affective disorder, currently manic diagnostic res36: Bipolar disorder
E114000 Read Bipolar affective disorder, currently manic, unspecified diagnostic res36: Bipolar disorder
E114100 Read Bipolar affective disorder, currently manic, mild diagnostic res36: Bipolar disorder
E114.11 Read Manic-depressive - now manic diagnostic res36: Bipolar disorder
E114200 Read Bipolar affective disorder, currently manic, moderate diagnostic res36: Bipolar disorder
E114300 Read Bipolar affect disord, currently manic, severe, no psychosis diagnostic res36: Bipolar disorder
E114400 Read Bipolar affect disord, currently manic,severe with psychosis diagnostic res36: Bipolar disorder
E114500 Read Bipolar affect disord,currently manic, part/unspec remission diagnostic res36: Bipolar disorder
E114600 Read Bipolar affective disorder, currently manic, full remission diagnostic res36: Bipolar disorder
E114z00 Read Bipolar affective disorder, currently manic, NOS diagnostic res36: Bipolar disorder
E115.00 Read Bipolar affective disorder, currently depressed diagnostic res36: Bipolar disorder
E115000 Read Bipolar affective disorder, currently depressed, unspecified diagnostic res36: Bipolar disorder
E115100 Read Bipolar affective disorder, currently depressed, mild diagnostic res36: Bipolar disorder
E115.11 Read Manic-depressive - now depressed diagnostic res36: Bipolar disorder
E115200 Read Bipolar affective disorder, currently depressed, moderate diagnostic res36: Bipolar disorder
E115300 Read Bipolar affect disord, now depressed, severe, no psychosis diagnostic res36: Bipolar disorder
E115400 Read Bipolar affect disord, now depressed, severe with psychosis diagnostic res36: Bipolar disorder
E115500 Read Bipolar affect disord, now depressed, part/unspec remission diagnostic res36: Bipolar disorder
E115600 Read Bipolar affective disorder, now depressed, in full remission diagnostic res36: Bipolar disorder
E115z00 Read Bipolar affective disorder, currently depressed, NOS diagnostic res36: Bipolar disorder
E116.00 Read Mixed bipolar affective disorder diagnostic res36: Bipolar disorder
E116000 Read Mixed bipolar affective disorder, unspecified diagnostic res36: Bipolar disorder
E116100 Read Mixed bipolar affective disorder, mild diagnostic res36: Bipolar disorder
E116200 Read Mixed bipolar affective disorder, moderate diagnostic res36: Bipolar disorder
E116300 Read Mixed bipolar affective disorder, severe, without psychosis diagnostic res36: Bipolar disorder
E116400 Read Mixed bipolar affective disorder, severe, with psychosis diagnostic res36: Bipolar disorder
E116500 Read Mixed bipolar affective disorder, partial/unspec remission diagnostic res36: Bipolar disorder
E116600 Read Mixed bipolar affective disorder, in full remission diagnostic res36: Bipolar disorder
E116z00 Read Mixed bipolar affective disorder, NOS diagnostic res36: Bipolar disorder
E117.00 Read Unspecified bipolar affective disorder diagnostic res36: Bipolar disorder
E117000 Read Unspecified bipolar affective disorder, unspecified diagnostic res36: Bipolar disorder
E117100 Read Unspecified bipolar affective disorder, mild diagnostic res36: Bipolar disorder
E117200 Read Unspecified bipolar affective disorder, moderate diagnostic res36: Bipolar disorder
E117300 Read Unspecified bipolar affective disorder, severe, no psychosis diagnostic res36: Bipolar disorder
E117400 Read Unspecified bipolar affective disorder,severe with psychosis diagnostic res36: Bipolar disorder
E117500 Read Unspecified bipolar affect disord, partial/unspec remission diagnostic res36: Bipolar disorder
E117600 Read Unspecified bipolar affective disorder, in full remission diagnostic res36: Bipolar disorder
E117z00 Read Unspecified bipolar affective disorder, NOS diagnostic res36: Bipolar disorder
E11y.00 Read Other and unspecified manic-depressive psychoses diagnostic res36: Bipolar disorder
E11y000 Read Unspecified manic-depressive psychoses diagnostic res36: Bipolar disorder
E11y100 Read Atypical manic disorder diagnostic res36: Bipolar disorder
E11y300 Read Other mixed manic-depressive psychoses diagnostic res36: Bipolar disorder
E11yz00 Read Other and unspecified manic-depressive psychoses NOS diagnostic res36: Bipolar disorder
Eu3..00 Read [X]Mood - affective disorders diagnostic res36: Bipolar disorder
Eu30.00 Read [X]Manic episode diagnostic res36: Bipolar disorder
Eu30000 Read [X]Hypomania diagnostic res36: Bipolar disorder
Eu30100 Read [X]Mania without psychotic symptoms diagnostic res36: Bipolar disorder
Eu30.11 Read [X]Bipolar disorder, single manic episode diagnostic res36: Bipolar disorder
Eu30200 Read [X]Mania with psychotic symptoms diagnostic res36: Bipolar disorder
Eu30211 Read [X]Mania with mood-congruent psychotic symptoms diagnostic res36: Bipolar disorder
Eu30212 Read [X]Mania with mood-incongruent psychotic symptoms diagnostic res36: Bipolar disorder
Eu30y00 Read [X]Other manic episodes diagnostic res36: Bipolar disorder
Eu30z00 Read [X]Manic episode, unspecified diagnostic res36: Bipolar disorder
Eu30z11 Read [X]Mania NOS diagnostic res36: Bipolar disorder
Eu31.00 Read [X]Bipolar affective disorder diagnostic res36: Bipolar disorder
Eu31000 Read [X]Bipolar affective disorder, current episode hypomanic diagnostic res36: Bipolar disorder
Eu31100 Read [X]Bipolar affect disorder cur epi manic wout psychotic symp diagnostic res36: Bipolar disorder
Eu31.11 Read [X]Manic-depressive illness diagnostic res36: Bipolar disorder
Eu31.12 Read [X]Manic-depressive psychosis diagnostic res36: Bipolar disorder
Eu31.13 Read [X]Manic-depressive reaction diagnostic res36: Bipolar disorder
Eu31200 Read [X]Bipolar affect disorder cur epi manic with psychotic symp diagnostic res36: Bipolar disorder
Eu31300 Read [X]Bipolar affect disorder cur epi mild or moderate depressn diagnostic res36: Bipolar disorder
Eu31400 Read [X]Bipol aff disord, curr epis sev depress, no psychot symp diagnostic res36: Bipolar disorder
Eu31500 Read [X]Bipolar affect dis cur epi severe depres with psyc symp diagnostic res36: Bipolar disorder
Eu31600 Read [X]Bipolar affective disorder, current episode mixed diagnostic res36: Bipolar disorder
Eu31700 Read [X]Bipolar affective disorder, currently in remission diagnostic res36: Bipolar disorder
Eu31y00 Read [X]Other bipolar affective disorders diagnostic res36: Bipolar disorder
Eu31y11 Read [X]Bipolar II disorder diagnostic res36: Bipolar disorder
Eu31y12 Read [X]Recurrent manic episodes diagnostic res36: Bipolar disorder
Eu31z00 Read [X]Bipolar affective disorder, unspecified diagnostic res36: Bipolar disorder
Eu33213 Read [X]Manic-depress psychosis,depressd,no psychotic symptoms diagnostic res36: Bipolar disorder
Eu33312 Read [X]Manic-depress psychosis,depressed type+psychotic symptoms diagnostic res36: Bipolar disorder
Eu34.00 Read [X]Persistent mood affective disorders diagnostic res36: Bipolar disorder
Eu34000 Read [X]Cyclothymia diagnostic res36: Bipolar disorder
Eu34y00 Read [X]Other persistent mood affective disorders diagnostic res36: Bipolar disorder
Eu34z00 Read [X]Persistent mood affective disorder, unspecified diagnostic res36: Bipolar disorder
Eu3y.00 Read [X]Other mood affective disorders diagnostic res36: Bipolar disorder
Eu3y000 Read [X]Other single mood affective disorders diagnostic res36: Bipolar disorder
Eu3y011 Read [X]Mixed affective episode diagnostic res36: Bipolar disorder
Eu3y100 Read [X]Other recurrent mood affective disorders diagnostic res36: Bipolar disorder
Eu3yy00 Read [X]Other specified mood affective disorders diagnostic res36: Bipolar disorder
Eu3z.00 Read [X]Unspecified mood affective disorder diagnostic res36: Bipolar disorder
Eu3z.11 Read [X]Affective psychosis NOS diagnostic res36: Bipolar disorder
ZV11111 Read [V]Personal history of manic-depressive psychosis diagnostic res36: Bipolar disorder
ZV11112 Read [V]Personal history of manic-depressive psychosis diagnostic res36: Bipolar disorder

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