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Research article:
HbA1C variability and hypoglycemia hospitalization in adults with type 1 and type 2 diabetes: a nested case-control study
Reference:
Victor W. Zhong; Juhaeri Juhaeri; Stephen R. Cole; Christina M. Shay; Penny Gordon-Larsen; Evangelos Kontopantelis; Elizabeth J Mayer-Davis(2017) HbA1C variability and hypoglycemia hospitalization in adults with type 1 and type 2 diabetes: a nested case-control study. Journal of Diabetes and its Complications, doi: http://dx.doi.org/10.1016/j.jdiacomp.2017.10.008
- Link to article
- Abstract
- Aims: To determine association between HbA1C variability and hypoglycemia requiring hospitalization (HH) in adults with type 1 diabetes (T1D) and type 2 diabetes (T2D). Methods: Using nested case-control design in electronic health record data in England, one case with first or recurrent HH was matched to one control who had not experienced HH in incident T1D and T2D adults. HbA1C variability was determined by standard deviation of ≥3 HbA1C results. Conditional logistic models were applied to determine association of HbA1C variability with first and recurrent HH. Results: In T1D, every 1.0% increase in HbA1C variability was associated with 90% higher first HH risk (95% CI, 1.25-2.89) and 392% higher recurrent HH risk (95% CI, 1.17- 20.61). In T2D, a 1.0% increase in HbA1C variability was associated with 556% higher first HH risk (95% CI, 3.88-11.08) and 573% higher recurrent HH risk (95% CI, 1.59-28.51). In T2D for first HH, the association was the strongest in non-insulin non-sulfonylurea users (P<0.0001); for recurrent HH, the association was stronger in insulin users than sulfonylurea users (P=0.07). The HbA1C variability-HH association was stronger in more recent years in T2D (P≤0.004). Conclusions: HbA1C variability is a strong predictor for HH in T1D and T2D.
- Author for correspondence
- Elizabeth J Mayer-Davis
- Email for correspondence
- mayerdav@email.unc.edu
Code list: res50: alpha-blockers
168 codes in list
| Code | Coding system | Description | Entity type | List name | drugsubstance | bnfcode | bnfchapter |
|---|---|---|---|---|---|---|---|
| 10088 | CPRD_product_code | Doxadura 4mg tablets (Discovery Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 10134 | CPRD_product_code | Flomaxtra XL 400microgram tablets (Astellas Pharma Ltd) | drug | res50: alpha-blockers | Tamsulosin Hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 11394 | CPRD_product_code | Baratol 25mg Tablet (Shire Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Indoramin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 119 | CPRD_product_code | Doxazosin 1mg tablets | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 12545 | CPRD_product_code | Phentolamine 10mg/1ml solution for injection ampoules | drug | res50: alpha-blockers | Phentolamine mesilate | 2050400 | Alpha-adrenoceptor Blocking Drugs |
| 1292 | CPRD_product_code | Hypovase 1mg tablets (Pfizer Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 1294 | CPRD_product_code | Doxazosin 4mg tablets | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 13610 | CPRD_product_code | Alphavase 2 tablets (Ashbourne Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 1455 | CPRD_product_code | Prazosin 500microgram tablets | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 14932 | CPRD_product_code | Tabphyn MR 400microgram capsules (ProStrakan Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 16198 | CPRD_product_code | Baratol 50mg Tablet (Shire Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Indoramin Hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 16201 | CPRD_product_code | Hytrin bph 2mg Tablet (Amdipharm Plc) | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 19193 | CPRD_product_code | Doxazosin 2mg tablets (Teva UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 19216 | CPRD_product_code | Doxazosin 4mg tablets (IVAX Pharmaceuticals UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders |
| 19823 | CPRD_product_code | Alphavase 5 tablets (Ashbourne Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 20369 | CPRD_product_code | Doxazosin 1mg/5ml oral suspension | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 2088 | CPRD_product_code | Alfuzosin 2.5mg tablets | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 2117 | CPRD_product_code | Doralese Tiltab 20mg tablets (Chemidex Pharma Ltd) | drug | res50: alpha-blockers | Indoramin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 2120 | CPRD_product_code | Alfuzosin 5mg modified-release tablets | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 23010 | CPRD_product_code | Rogitine 10mg/1ml solution for injection ampoules (Alliance Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Phentolamine mesilate | 2050400 | Alpha-adrenoceptor Blocking Drugs |
| 2345 | CPRD_product_code | Hytrin BPH tablets starter pack (AMCo) | drug | res50: alpha-blockers | 7040150 | Alpha-blockers (in Urinary Retention) | |
| 23459 | CPRD_product_code | Hypovase benign prostatic hyperplasia 2mg Tablet (Pfizer Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 2346 | CPRD_product_code | Hytrin 5mg Tablet (Abbott Laboratories Ltd) | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 2347 | CPRD_product_code | Hytrin 10mg Tablet (Abbott Laboratories Ltd) | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 2348 | CPRD_product_code | Hytrin bph 10mg Tablet (Amdipharm Plc) | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 24369 | CPRD_product_code | Petyme 400microgram MR capsules (Teva UK Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 25047 | CPRD_product_code | Hypovase benign prostatic hyperplasia 500microgram Tablet (Pfizer Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 25487 | CPRD_product_code | Cascor 2mg tablets (Ranbaxy (UK) Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders |
| 25551 | CPRD_product_code | Cascor 4mg tablets (Ranbaxy (UK) Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders |
| 26237 | CPRD_product_code | Alphavase 500microgram Tablet (Ashbourne Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 26238 | CPRD_product_code | Alphavase 1 tablets (Ashbourne Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 26693 | CPRD_product_code | Hypovase benign prostatic hyperplasia bd BD Starter pack (Pfizer Ltd) | drug | res50: alpha-blockers | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) | |
| 27403 | CPRD_product_code | Omnic MR 400microgram capsules (Astellas Pharma Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 2816 | CPRD_product_code | Indoramin 20mg tablets | drug | res50: alpha-blockers | Indoramin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 28441 | CPRD_product_code | Pamsvax XL 400microgram capsules (Actavis UK Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 31109 | CPRD_product_code | Prosurin XL 400microgram capsules (Generics (UK) Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 33094 | CPRD_product_code | Doxazosin 2mg tablets (Generics (UK) Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 34080 | CPRD_product_code | Stronazon 400microgram MR capsules (Actavis UK Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 34342 | CPRD_product_code | Doxazosin 1mg tablets (Teva UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 34553 | CPRD_product_code | Doxazosin 4mg tablets (Generics (UK) Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 34601 | CPRD_product_code | Doxazosin 1mg tablets (Generics (UK) Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 34625 | CPRD_product_code | Doxazosin 2mg tablets (A A H Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 3470 | CPRD_product_code | Terazosin 1mg tablets | drug | res50: alpha-blockers | Terazosine | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 34715 | CPRD_product_code | Doxazosin 1mg tablets (A A H Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 35058 | CPRD_product_code | Diffundox XL 400microgram capsules (Zentiva) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 35272 | CPRD_product_code | Doxadura XL 4mg tablets (Discovery Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 35312 | CPRD_product_code | Bazetham MR 400microgram capsules (Teva UK Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 35466 | CPRD_product_code | Alphacard MR 400microgram capsules (Ratiopharm UK Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 35603 | CPRD_product_code | Doxazosin 4mg/5ml oral suspension | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 35639 | CPRD_product_code | Besavar XL 10mg tablets (Zentiva) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 35925 | CPRD_product_code | Contiflo XL 400microgram capsules (Ranbaxy (UK) Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 36023 | CPRD_product_code | Cardozin xl 4mg Tablet (Hillcross Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 36282 | CPRD_product_code | Morvesin XL 400microgram capsules (Sandoz Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 36439 | CPRD_product_code | Zufal XL 10mg tablets (Teva UK Ltd) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 36649 | CPRD_product_code | Hytrin 2mg tablets (AMCo) | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 36740 | CPRD_product_code | Slocinx XL 4mg tablets (Zentiva) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 36780 | CPRD_product_code | Hytrin 5mg tablets (AMCo) | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 3715 | CPRD_product_code | Prazosin 5mg tablets | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 37243 | CPRD_product_code | Cardozin xl 4mg Tablet (Teva UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 37428 | CPRD_product_code | Hytrin 10mg tablets (AMCo) | drug | res50: alpha-blockers | Terazosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 38461 | CPRD_product_code | Cardozin XL 4mg tablets (Arrow Generics Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 3923 | CPRD_product_code | Terazosin BPH starter pack 7x1mg with 14x2mg with 7x5mg | drug | res50: alpha-blockers | Terazosine | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 3924 | CPRD_product_code | Terazosin 5mg tablets | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 39373 | CPRD_product_code | Fuzatal XL 10mg tablets (Teva UK Ltd) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 40256 | CPRD_product_code | Baratol 25mg tablets (Amdipharm Plc) | drug | res50: alpha-blockers | Indoramin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 40678 | CPRD_product_code | Doxazosin 4mg tablets (Teva UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders |
| 40810 | CPRD_product_code | Phenoxybenzamine 10mg/5ml oral suspension | drug | res50: alpha-blockers | Phenoxybenzamine hydrochloride | 2050400 | Alpha-adrenoceptor Blocking Drugs |
| 40891 | CPRD_product_code | Doxazosin 2mg tablets (IVAX Pharmaceuticals UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders |
| 4111 | CPRD_product_code | Hypovase 500microgram tablets (Pfizer Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 41543 | CPRD_product_code | Doxazosin 1mg tablets (IVAX Pharmaceuticals UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders |
| 41651 | CPRD_product_code | Prazosin 500microgram Tablet (Approved Prescription Services Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 41652 | CPRD_product_code | Prazosin 500microgram tablets (A A H Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 41721 | CPRD_product_code | Prazosin 1mg tablets (A A H Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 42462 | CPRD_product_code | Kirtacap mr 400microgram Capsule (Consilient Health Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 42820 | CPRD_product_code | Alfuzosin xl 10mg Tablet (Hillcross Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 42936 | CPRD_product_code | Flomax Relief MR 400microgram capsules (Boehringer Ingelheim Self-Medication Divi | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 43458 | CPRD_product_code | Tamsulosin 400microgram / Dutasteride 500microgram capsules | drug | res50: alpha-blockers | Tamsulosin Hydrochloride/dutasteride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 43547 | CPRD_product_code | Prazosin 500microgram tablets (IVAX Pharmaceuticals UK Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 43567 | CPRD_product_code | Combodart 0.5mg/0.4mg capsules (GlaxoSmithKline UK Ltd) | drug | res50: alpha-blockers | Tamsulosin Hydrochloride/dutasteride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 43695 | CPRD_product_code | Colixil XL 4mg tablets (Sandoz Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 44268 | CPRD_product_code | Vasran XL 10mg tablets (Ranbaxy (UK) Ltd) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 4449 | CPRD_product_code | Cardura 1mg tablets (Pfizer Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 44553 | CPRD_product_code | Pinexel PR 400microgram capsules (Wockhardt UK Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 45040 | CPRD_product_code | Larbex XL 4mg tablets (Teva UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 45265 | CPRD_product_code | Doxazosin sr 4mg Tablet (Generics (UK) Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 45328 | CPRD_product_code | Doxazosin 1mg tablets (Sandoz Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders |
| 45342 | CPRD_product_code | Doxazosin 4mg tablets (Sandoz Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders |
| 45583 | CPRD_product_code | Doxazosin 2mg tablets (Dexcel-Pharma Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 45584 | CPRD_product_code | Phenoxybenzamine 100mg/2ml solution for infusion ampoules | drug | res50: alpha-blockers | Phenoxybenzamine hydrochloride | 2050400 | Alpha-adrenoceptor Blocking Drugs |
| 460 | CPRD_product_code | Flomax MR 400microgram capsules (Astellas Pharma Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 46066 | CPRD_product_code | Cardozin XL 4mg tablets (Almus Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 46206 | CPRD_product_code | Pamsvax XL 400microgram capsules (Almus Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 4637 | CPRD_product_code | Terazosin 2mg tablets | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 46526 | CPRD_product_code | Raporsin XL 4mg tablets (Actavis UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 46922 | CPRD_product_code | Prazosin 1mg tablets (IVAX Pharmaceuticals UK Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 4694 | CPRD_product_code | Terazosin 2mg tablets and Terazosin 1mg tablets | drug | res50: alpha-blockers | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) | |
| 47563 | CPRD_product_code | Besavar XL 10mg tablets (Actavis UK Ltd) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 47807 | CPRD_product_code | Doxazosin xl 4mg Tablet (Hillcross Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 4802 | CPRD_product_code | Cardura 2mg tablets (Pfizer Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 48150 | CPRD_product_code | Doxazosin 1mg tablets (Actavis UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 4875 | CPRD_product_code | Terazosin 10mg tablets | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 493 | CPRD_product_code | Doxazosin 2mg tablets | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 50467 | CPRD_product_code | Doxazosin 2mg tablets (Alliance Healthcare (Distribution) Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 51665 | CPRD_product_code | Tamurex 400microgram modified-release capsules (Somex Pharma) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 51685 | CPRD_product_code | Doxazosin 4mg tablets (Actavis UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 5179 | CPRD_product_code | Xatral XL 10mg tablets (Sanofi) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 5183 | CPRD_product_code | Hypovase 2mg tablets (Pfizer Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 52055 | CPRD_product_code | Tamsulosin 400microgram oral powder sachets | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 52159 | CPRD_product_code | Tamsulosin 400microgram modified-release capsules (Focus Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 53033 | CPRD_product_code | Doxzogen XL 4mg tablets (Generics (UK) Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 53084 | CPRD_product_code | Cositam XL 400microgram tablets (Consilient Health Ltd) | drug | res50: alpha-blockers | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) | |
| 53322 | CPRD_product_code | Doxazosin 4mg tablets (Bristol Laboratories Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 5337 | CPRD_product_code | Hytrin bph 5mg Tablet (Amdipharm Plc) | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 53964 | CPRD_product_code | Tamsulosin 400microgram modified-release capsules (A A H Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 54497 | CPRD_product_code | Galebon 400microgram modified-release capsules (Consilient Health Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 54785 | CPRD_product_code | Doxazosin 4mg tablets (Medreich Plc) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders |
| 5485 | CPRD_product_code | Alfuzosin 10mg modified-release tablets | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 54918 | CPRD_product_code | Phenoxybenzamine oral liquid | drug | res50: alpha-blockers | Phenoxybenzamine Hydrochloride | 2050400 | Alpha-adrenoceptor Blocking Drugs |
| 5496 | CPRD_product_code | Doxazosin 8mg modified-release tablets | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 55005 | CPRD_product_code | Kelanu XL 10mg tablets (Pfizer Ltd) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 55826 | CPRD_product_code | Prazosin 5mg tablets (A A H Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 55906 | CPRD_product_code | Doxazosin 1mg tablets (Dexcel-Pharma Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 55916 | CPRD_product_code | Doxazosin 1mg tablets (Alliance Healthcare (Distribution) Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 56145 | CPRD_product_code | Doxazosin 2mg tablets (Actavis UK Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 5618 | CPRD_product_code | Cardura XL 8mg tablets (Pfizer Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 5624 | CPRD_product_code | Xatral 2.5mg tablets (Sanofi) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 56793 | CPRD_product_code | Alfuzosin 2.5mg tablets (Teva UK Ltd) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 57074 | CPRD_product_code | Doxazosin 2mg tablets (Sigma Pharmaceuticals Plc) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 57145 | CPRD_product_code | Terazosin 2mg tablets (A A H Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 57448 | CPRD_product_code | Doxazosin 4mg tablets (A A H Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000/07 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders/Alpha-blockers |
| 57549 | CPRD_product_code | Xatral 2.5mg tablets (Necessity Supplies Ltd) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 57784 | CPRD_product_code | Doxazosin 2mg/5ml oral suspension | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 5815 | CPRD_product_code | Indoramin 25mg tablets | drug | res50: alpha-blockers | Indoramin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 582 | CPRD_product_code | Doxazosin 4mg modified-release tablets | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 58276 | CPRD_product_code | Doxazosin 2mg tablets (Medreich Plc) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 58325 | CPRD_product_code | Doxazosin 4mg tablets (Phoenix Healthcare Distribution Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040000 | Alpha-adrenoceptor Blocking Drugs/Drugs For Genito-urinary Disorders |
| 58517 | CPRD_product_code | Faramsil 400microgram modified-release tablets (Sandoz Ltd) | drug | res50: alpha-blockers | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) | |
| 58985 | CPRD_product_code | Xatral SR 5mg tablets (Sanofi-Synthelabo Ltd) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
| 591 | CPRD_product_code | Prazosin 1mg tablets | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 59209 | CPRD_product_code | Doxazosin 1mg tablets (Kent Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 59462 | CPRD_product_code | Vesomni 6mg/0.4mg modified-release tablets (Astellas Pharma Ltd) | drug | res50: alpha-blockers | 07040150/07040250 | Alpha-blockers (in Urinary Retention)/Urinary Incontinence | |
| 59676 | CPRD_product_code | Solifenacin 6mg / Tamsulosin 400microgram modified-release tablets | drug | res50: alpha-blockers | 07040150/07040250 | Alpha-blockers (in Urinary Retention)/Urinary Incontinence | |
| 59862 | CPRD_product_code | Doxazosin 4mg tablets (Dexcel-Pharma Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 6008 | CPRD_product_code | Omnic 400microgram Modified-release capsule (Paines & Byrne Ltd) | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 60200 | CPRD_product_code | Doxazosin 4mg tablets (DE Pharmaceuticals) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 60316 | CPRD_product_code | Prazosin 1mg Tablet (Approved Prescription Services Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 60319 | CPRD_product_code | Doxazosin 1mg tablets (Bristol Laboratories Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 61066 | CPRD_product_code | Doxazosin 2mg tablets (Bristol Laboratories Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 61123 | CPRD_product_code | Doxazosin 4mg/5ml oral solution | drug | res50: alpha-blockers | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) | |
| 61283 | CPRD_product_code | Doxazosin 4mg tablets (Alliance Healthcare (Distribution) Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 61844 | CPRD_product_code | Invicorp 2 solution for injection (Senetek Plc) | drug | res50: alpha-blockers | Aviptadil/Phentolamine mesilate | 7040500 | Drugs For Erectile Dysfunction |
| 62019 | CPRD_product_code | Doxazosin 1mg tablets (Almus Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 62158 | CPRD_product_code | Doxazosin 4mg tablets (Almus Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 634 | CPRD_product_code | Tamsulosin 400microgram modified-release capsules | drug | res50: alpha-blockers | Tamsulosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 7056 | CPRD_product_code | Tamsulosin 400microgram modified-release tablets | drug | res50: alpha-blockers | Tamsulosin Hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 726 | CPRD_product_code | Prazosin 2mg tablets | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 7547 | CPRD_product_code | Doxadura 2mg tablets (Discovery Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 7549 | CPRD_product_code | Doxadura 1mg tablets (Discovery Pharmaceuticals Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 755 | CPRD_product_code | Cardura XL 4mg tablets (Pfizer Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 7759 | CPRD_product_code | Phenoxybenzamine 10mg capsules | drug | res50: alpha-blockers | Phenoxybenzamine hydrochloride | 2050400 | Alpha-adrenoceptor Blocking Drugs |
| 8076 | CPRD_product_code | Hytrin tablets starter pack (AMCo) | drug | res50: alpha-blockers | 7040150 | Alpha-blockers (in Urinary Retention) | |
| 8077 | CPRD_product_code | Hytrin 2mg Tablet (Abbott Laboratories Ltd) | drug | res50: alpha-blockers | Terazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 8086 | CPRD_product_code | Cardura 4mg Tablet (Pfizer Ltd) | drug | res50: alpha-blockers | Doxazosin mesilate | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 8198 | CPRD_product_code | Hypovase 5mg Tablet (Pfizer Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 8863 | CPRD_product_code | Hypovase benign prostatic hyperplasia 1mg Tablet (Pfizer Ltd) | drug | res50: alpha-blockers | Prazosin hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 8942 | CPRD_product_code | Dibenyline 10mg capsules (Mercury Pharma Group Ltd) | drug | res50: alpha-blockers | Phenoxybenzamine hydrochloride | 2050400 | Alpha-adrenoceptor Blocking Drugs |
| 9019 | CPRD_product_code | Indoramin 50mg Tablet | drug | res50: alpha-blockers | Indoramin Hydrochloride | 02050400/07040150 | Alpha-adrenoceptor Blocking Drugs/Alpha-blockers (in Urinary Retention) |
| 9422 | CPRD_product_code | Xatral sr 5mg Tablet (Sanofi-Synthelabo Ltd) | drug | res50: alpha-blockers | Alfuzosin hydrochloride | 7040150 | Alpha-blockers (in Urinary Retention) |
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ClinicalCodes is a project at the University of Manchester Institute of Population Health
The ClinicalCodes project is funded by the National Institute for Health Research (NIHR) School for Primary Care Research (SPCR)