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Research article:

Incidence, clinical management, and mortality risk following self-harm among children and adolescents: cohort study in primary care

Reference:

C Morgan, RT Webb, MJ Carr, E Kontopantelis, J Green, CA Chew-Graham, N Kapur, DM Ashcroft (2017) Incidence, clinical management, and mortality risk following self-harm among children and adolescents: cohort study in primary care. The BMJ, doi: doi.org/10.1136/bmj.j4351

Link to fulltext article
Abstract
Abstract Objectives To examine temporal trends in sex and age specific incidence of self harm in children and adolescents, clinical management patterns, and risk of cause specific mortality following an index self harm episode at a young age. Design Population based cohort study. Setting UK Clinical Practice Research Datalink—electronic health records from 674 general practices, with practice level deprivation measured ecologically using the index of multiple deprivation. Patients from eligible English practices were linked to hospital episode statistics (HES) and Office for National Statistics (ONS) mortality records. Participants For the descriptive analytical phases we examined data pertaining to 16 912 patients aged 10-19 who harmed themselves during 2001-14. For analysis of cause specific mortality following self harm, 8638 patients eligible for HES and ONS linkage were matched by age, sex, and general practice with up to 20 unaffected children and adolescents (n=170 274). Main outcome measures In the first phase, temporal trends in sex and age specific annual incidence were examined. In the second phase, clinical management was assessed according to the likelihood of referral to mental health services and psychotropic drug prescribing. In the third phase, relative risks of all cause mortality, unnatural death (including suicide and accidental death), and fatal acute alcohol or drug poisoning were estimated as hazard ratios derived from stratified Cox proportional hazards models for the self harm cohort versus the matched unaffected comparison cohort. Results The annual incidence of self harm was observed to increase in girls (37.4 per 10 000) compared with boys (12.3 per 10 000), and a sharp 68% increase occurred among girls aged 13-16, from 45.9 per 10 000 in 2011 to 77.0 per 10 000 in 2014. Referrals within 12 months of the index self harm episode were 23% less likely for young patients registered at the most socially deprived practices, even though incidences were considerably higher in these localities. Children and adolescents who harmed themselves were approximately nine times more likely to die unnaturally during follow-up, with especially noticeable increases in risks of suicide (deprivation adjusted hazard ratio 17.5, 95% confidence interval 7.6 to 40.5) and fatal acute alcohol or drug poisoning (34.3, 10.2 to 115.7). Conclusions Gaining a better understanding of the mechanisms responsible for the recent apparent increase in the incidence of self harm among early-mid teenage girls, and coordinated initiatives to tackle health inequalities in the provision of services to distressed children and adolescents, represent urgent priorities for multiple public agencies.
Author for correspondence
Catharine Morgan
Email for correspondence
cathy.morgan@manchester.ac.uk

Code list: res59: Eating_disorder

41 codes in list

Code Coding system Description Entity type List name
1612.00 Read Appetite loss - anorexia diagnostic res59: Eating_disorder
1612.11 Read Anorexia symptom diagnostic res59: Eating_disorder
1614.00 Read Excessive eating - polyphagia diagnostic res59: Eating_disorder
1614.11 Read Hyperalimentation - symptom diagnostic res59: Eating_disorder
1614.12 Read Polyphagia symptom diagnostic res59: Eating_disorder
8HTN.00 Read Referral to eating disorders clinic diagnostic res59: Eating_disorder
9Nk9.00 Read Seen in eating disorder clinic diagnostic res59: Eating_disorder
E271.00 Read Anorexia nervosa diagnostic res59: Eating_disorder
E275.00 Read Other and unspecified non-organic eating disorders diagnostic res59: Eating_disorder
E275000 Read Unspecified non-organic eating disorder diagnostic res59: Eating_disorder
E275100 Read Bulimia (non-organic overeating) diagnostic res59: Eating_disorder
E275111 Read Compulsive eating disorder diagnostic res59: Eating_disorder
E275300 Read Psychogenic rumination diagnostic res59: Eating_disorder
E275400 Read Psychogenic vomiting NOS diagnostic res59: Eating_disorder
E275y00 Read Other specified non-organic eating disorder diagnostic res59: Eating_disorder
E275z00 Read Non-organic eating disorder NOS diagnostic res59: Eating_disorder
Eu50.00 Read [X]Eating disorders diagnostic res59: Eating_disorder
Eu50000 Read [X]Anorexia nervosa diagnostic res59: Eating_disorder
Eu50100 Read [X]Atypical anorexia nervosa diagnostic res59: Eating_disorder
Eu50200 Read [X]Bulimia nervosa diagnostic res59: Eating_disorder
Eu50211 Read [X]Bulimia NOS diagnostic res59: Eating_disorder
Eu50212 Read [X]Hyperorexia nervosa diagnostic res59: Eating_disorder
Eu50300 Read [X]Atypical bulimia nervosa diagnostic res59: Eating_disorder
Eu50400 Read [X]Overeating associated with other psychological disturbncs diagnostic res59: Eating_disorder
Eu50411 Read [X]Psychogenic overeating diagnostic res59: Eating_disorder
Eu50500 Read [X]Vomiting associated with other psychological disturbances diagnostic res59: Eating_disorder
Eu50511 Read [X]Psychogenic vomiting diagnostic res59: Eating_disorder
Eu50y00 Read [X]Other eating disorders diagnostic res59: Eating_disorder
Eu50z00 Read [X]Eating disorder; unspecified diagnostic res59: Eating_disorder
Fy05.00 Read Nocturnal sleep-related eating disorder diagnostic res59: Eating_disorder
R030.00 Read [D]Anorexia diagnostic res59: Eating_disorder
R030z00 Read [D]Anorexia NOS diagnostic res59: Eating_disorder
R036.00 Read [D]Polyphagia diagnostic res59: Eating_disorder
R036000 Read [D]Excessive eating diagnostic res59: Eating_disorder
R036011 Read [D]Bulimia NOS diagnostic res59: Eating_disorder
R036100 Read [D]Hyperalimentation diagnostic res59: Eating_disorder
R036z00 Read [D]Polyphagia NOS diagnostic res59: Eating_disorder
SN42100 Read Starvation diagnostic res59: Eating_disorder
U1B3.11 Read [X]Starvation diagnostic res59: Eating_disorder
Z4B5.00 Read Eating disorder counselling diagnostic res59: Eating_disorder
ZC2CD00 Read Dietary advice for eating disorder diagnostic res59: Eating_disorder

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