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Research article:
Landmark Models for Optimizing the Use of Repeated Measurements of Risk Factors in Electronic Health Records to Predict Future Disease Risk
Reference:
Ellie Paige, Jessica Barrett, David Stevens, Ruth H. Keogh, Michael J. Sweeting, Irwin Nazareth, Irene Petersen, and Angela M. Wood(2018) Landmark Models for Optimizing the Use of Repeated Measurements of Risk Factors in Electronic Health Records to Predict Future Disease Risk. American Journal of Epidemiology, doi: 10.1093/aje/kwy018
- Link to article
- Abstract
- The benefits of using electronic health records (EHRs) for disease risk screening and personalized health-care decisions are being increasingly recognized. Here we present a computationally feasible statistical approach with which to address the methodological challenges involved in utilizing historical repeat measures of multiple risk factors recorded in EHRs to systematically identify patients at high risk of future disease. The approach is principally based on a 2-stage dynamic landmark model. The first stage estimates current risk factor values from all available historical repeat risk factor measurements via landmark-age–specific multivariate linear mixed-effects models with correlated random intercepts, which account for sporadically recorded repeat measures, unobserved data, and measurement errors. The second stage predicts future disease risk from a sex-stratified Cox proportional hazardsmodel, with estimated current risk factor values from the first stage.We exemplify thesemethods by developing and validating a dynamic 10-year cardiovascular disease risk prediction model using primary-care EHRs for age, diabetes status, hypertension treatment, smoking status, systolic blood pressure, total cholesterol, and high-density lipoprotein cholesterol in 41,373 persons from 10 primary-care practices in England andWales contributing to The Health Improvement Network (1997–2016). Using cross-validation, the model was well-calibrated (Brier score = 0.041, 95% confidence interval: 0.039, 0.042) and had good discrimination (C-index = 0.768, 95%confidence interval: 0.759, 0.777).
- Author for correspondence
- Angela Wood
- Email for correspondence
- amw79@medschl.cam.ac.uk
Code list: res67: CVD_Read_Code
352 codes in list
| Code | Coding system | Description | Entity type | List name | |||
|---|---|---|---|---|---|---|---|
| 14A3.00 | Read | H/O: myocardial infarct <60 | diagnostic | res67: CVD_Read_Code | |||
| 14A4.00 | Read | H/O: myocardial infarct >60 | diagnostic | res67: CVD_Read_Code | |||
| 14A5.00 | Read | H/O: angina pectoris | diagnostic | res67: CVD_Read_Code | |||
| 14A7.00 | Read | H/O: CVA/stroke | diagnostic | res67: CVD_Read_Code | |||
| 14A7.11 | Read | H/O: CVA | diagnostic | res67: CVD_Read_Code | |||
| 14A7.12 | Read | H/O: stroke | diagnostic | res67: CVD_Read_Code | |||
| 14AB.00 | Read | H/O: TIA | diagnostic | res67: CVD_Read_Code | |||
| 14AH.00 | Read | H/O: Myocardial infarction in last year | diagnostic | res67: CVD_Read_Code | |||
| 14AJ.00 | Read | H/O: Angina in last year | diagnostic | res67: CVD_Read_Code | |||
| 14AK.00 | Read | H/O: Stroke in last year | diagnostic | res67: CVD_Read_Code | |||
| 14AT.00 | Read | History of myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| 322..00 | Read | ECG: myocardial ischaemia | diagnostic | res67: CVD_Read_Code | |||
| 3222 | Read | ECG:shows myocardial ischaemia | diagnostic | res67: CVD_Read_Code | |||
| 322Z.00 | Read | ECG: myocardial ischaemia NOS | diagnostic | res67: CVD_Read_Code | |||
| 323..00 | Read | ECG: myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| 3232 | Read | ECG: old myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| 3233 | Read | ECG: antero-septal infarct. | diagnostic | res67: CVD_Read_Code | |||
| 3234 | Read | ECG:posterior/inferior infarct | diagnostic | res67: CVD_Read_Code | |||
| 3235 | Read | ECG: subendocardial infarct | diagnostic | res67: CVD_Read_Code | |||
| 3236 | Read | ECG: lateral infarction | diagnostic | res67: CVD_Read_Code | |||
| 323Z.00 | Read | ECG: myocardial infarct NOS | diagnostic | res67: CVD_Read_Code | |||
| 662K000 | Read | Angina control - good | diagnostic | res67: CVD_Read_Code | |||
| 662K100 | Read | Angina control - poor | diagnostic | res67: CVD_Read_Code | |||
| 662K200 | Read | Angina control - improving | diagnostic | res67: CVD_Read_Code | |||
| 662K300 | Read | Angina control - worsening | diagnostic | res67: CVD_Read_Code | |||
| 662Kz00 | Read | Angina control NOS | diagnostic | res67: CVD_Read_Code | |||
| 7920 | Read | Saphenous vein graft replacement of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 792..00 | Read | Coronary artery operations | diagnostic | res67: CVD_Read_Code | |||
| 7920000 | Read | Saphenous vein graft replacement of one coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7920100 | Read | Saphenous vein graft replacement of two coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7920.11 | Read | Saphenous vein graft bypass of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7920200 | Read | Saphenous vein graft replacement of three coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7920300 | Read | Saphenous vein graft replacement of four+ coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7920y00 | Read | Saphenous vein graft replacement of coronary artery OS | diagnostic | res67: CVD_Read_Code | |||
| 7920z00 | Read | Saphenous vein graft replacement coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 7921 | Read | Other autograft replacement of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7921000 | Read | Autograft replacement of one coronary artery NEC | diagnostic | res67: CVD_Read_Code | |||
| 792..11 | Read | Coronary artery bypass graft operations | diagnostic | res67: CVD_Read_Code | |||
| 7921100 | Read | Autograft replacement of two coronary arteries NEC | diagnostic | res67: CVD_Read_Code | |||
| 7921.11 | Read | Other autograft bypass of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7921200 | Read | Autograft replacement of three coronary arteries NEC | diagnostic | res67: CVD_Read_Code | |||
| 7921300 | Read | Autograft replacement of four of more coronary arteries NEC | diagnostic | res67: CVD_Read_Code | |||
| 7921y00 | Read | Other autograft replacement of coronary artery OS | diagnostic | res67: CVD_Read_Code | |||
| 7921z00 | Read | Other autograft replacement of coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 7922 | Read | Allograft replacement of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7922000 | Read | Allograft replacement of one coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7922100 | Read | Allograft replacement of two coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7922.11 | Read | Allograft bypass of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7922200 | Read | Allograft replacement of three coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7922300 | Read | Allograft replacement of four or more coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7922y00 | Read | Other specified allograft replacement of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7922z00 | Read | Allograft replacement of coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 7923 | Read | Prosthetic replacement of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7923000 | Read | Prosthetic replacement of one coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7923100 | Read | Prosthetic replacement of two coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7923.11 | Read | Prosthetic bypass of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7923200 | Read | Prosthetic replacement of three coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7923300 | Read | Prosthetic replacement of four or more coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7923y00 | Read | Other specified prosthetic replacement of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7923z00 | Read | Prosthetic replacement of coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 7924 | Read | Revision of bypass for coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7924000 | Read | Revision of bypass for one coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7924100 | Read | Revision of bypass for two coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7924200 | Read | Revision of bypass for three coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7924300 | Read | Revision of bypass for four or more coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7924400 | Read | Revision of connection of thoracic artery to coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7924500 | Read | Revision of implantation of thoracic artery into heart | diagnostic | res67: CVD_Read_Code | |||
| 7924y00 | Read | Other specified revision of bypass for coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7924z00 | Read | Revision of bypass for coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 7925 | Read | Connection of mammary artery to coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7925000 | Read | Double anastomosis of mammary arteries to coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7925011 | Read | LIMA sequential anastomosis | diagnostic | res67: CVD_Read_Code | |||
| 7925012 | Read | RIMA sequential anastomosis | diagnostic | res67: CVD_Read_Code | |||
| 7925100 | Read | Double implant of mammary arteries into coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7925.11 | Read | Creation of bypass from mammary artery to coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7925200 | Read | Single anast mammary art to left ant descend coronary art | diagnostic | res67: CVD_Read_Code | |||
| 7925300 | Read | Single anastomosis of mammary artery to coronary artery NEC | diagnostic | res67: CVD_Read_Code | |||
| 7925311 | Read | LIMA single anastomosis | diagnostic | res67: CVD_Read_Code | |||
| 7925312 | Read | RIMA single anastomosis | diagnostic | res67: CVD_Read_Code | |||
| 7925400 | Read | Single implantation of mammary artery into coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7925y00 | Read | Connection of mammary artery to coronary artery OS | diagnostic | res67: CVD_Read_Code | |||
| 7925z00 | Read | Connection of mammary artery to coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 7926 | Read | Connection of other thoracic artery to coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7926000 | Read | Double anastom thoracic arteries to coronary arteries NEC | diagnostic | res67: CVD_Read_Code | |||
| 7926100 | Read | Double implant thoracic arteries into coronary arteries NEC | diagnostic | res67: CVD_Read_Code | |||
| 7926200 | Read | Single anastomosis of thoracic artery to coronary artery NEC | diagnostic | res67: CVD_Read_Code | |||
| 7926300 | Read | Single implantation thoracic artery into coronary artery NEC | diagnostic | res67: CVD_Read_Code | |||
| 7926y00 | Read | Connection of other thoracic artery to coronary artery OS | diagnostic | res67: CVD_Read_Code | |||
| 7926z00 | Read | Connection of other thoracic artery to coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 7927300 | Read | Transposition of coronary artery NEC | diagnostic | res67: CVD_Read_Code | |||
| 7927400 | Read | Exploration of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7927500 | Read | Open angioplasty of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7927y00 | Read | Other specified other open operation on coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7927z00 | Read | Other open operation on coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 7928 | Read | Transluminal balloon angioplasty of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7928000 | Read | Percut transluminal balloon angioplasty one coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7928100 | Read | Percut translum balloon angioplasty mult coronary arteries | diagnostic | res67: CVD_Read_Code | |||
| 7928.11 | Read | Percutaneous balloon coronary angioplasty | diagnostic | res67: CVD_Read_Code | |||
| 7928200 | Read | Percut translum balloon angioplasty bypass graft coronary a | diagnostic | res67: CVD_Read_Code | |||
| 7928300 | Read | Percut translum cutting balloon angioplasty coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7928y00 | Read | Transluminal balloon angioplasty of coronary artery OS | diagnostic | res67: CVD_Read_Code | |||
| 7928z00 | Read | Transluminal balloon angioplasty of coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 7929 | Read | Other therapeutic transluminal operations on coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7929000 | Read | Percutaneous transluminal laser coronary angioplasty | diagnostic | res67: CVD_Read_Code | |||
| 7929100 | Read | Percut transluminal coronary thrombolysis with streptokinase | diagnostic | res67: CVD_Read_Code | |||
| 7929111 | Read | Percut translum coronary thrombolytic therapy- streptokinase | diagnostic | res67: CVD_Read_Code | |||
| 7929200 | Read | Percut translum inject therap subst to coronary artery NEC | diagnostic | res67: CVD_Read_Code | |||
| 7929300 | Read | Rotary blade coronary angioplasty | diagnostic | res67: CVD_Read_Code | |||
| 7929400 | Read | Insertion of coronary artery stent | diagnostic | res67: CVD_Read_Code | |||
| 7929500 | Read | Insertion of drug-eluting coronary artery stent | diagnostic | res67: CVD_Read_Code | |||
| 7929600 | Read | Percutaneous transluminal atherectomy of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 7929y00 | Read | Other therapeutic transluminal op on coronary artery OS | diagnostic | res67: CVD_Read_Code | |||
| 7929z00 | Read | Other therapeutic transluminal op on coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 792A.00 | Read | Diagnostic transluminal operations on coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 792Ay00 | Read | Diagnostic transluminal operation on coronary artery OS | diagnostic | res67: CVD_Read_Code | |||
| 792Az00 | Read | Diagnostic transluminal operation on coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 792B.00 | Read | Repair of coronary artery NEC | diagnostic | res67: CVD_Read_Code | |||
| 792B000 | Read | Endarterectomy of coronary artery NEC | diagnostic | res67: CVD_Read_Code | |||
| 792By00 | Read | Other specified repair of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 792Bz00 | Read | Repair of coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 792C.00 | Read | Other replacement of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 792C000 | Read | Replacement of coronary arteries using multiple methods | diagnostic | res67: CVD_Read_Code | |||
| 792Cy00 | Read | Other specified replacement of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 792Cz00 | Read | Replacement of coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 792D.00 | Read | Other bypass of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 792Dy00 | Read | Other specified other bypass of coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 792Dz00 | Read | Other bypass of coronary artery NOS | diagnostic | res67: CVD_Read_Code | |||
| 792y.00 | Read | Other specified operations on coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 792z.00 | Read | Coronary artery operations NOS | diagnostic | res67: CVD_Read_Code | |||
| 793G.00 | Read | Perc translumin balloon angioplasty stenting coronary artery | diagnostic | res67: CVD_Read_Code | |||
| 793G000 | Read | Perc translum ball angio insert 1-2 drug elut stents cor art | diagnostic | res67: CVD_Read_Code | |||
| 793G100 | Read | Perc tran ball angio ins 3 or more drug elut stents cor art | diagnostic | res67: CVD_Read_Code | |||
| 793G200 | Read | Perc translum balloon angioplasty insert 1-2 stents cor art | diagnostic | res67: CVD_Read_Code | |||
| 793G300 | Read | Percutaneous cor balloon angiop 3 more stents cor art NEC | diagnostic | res67: CVD_Read_Code | |||
| 793Gy00 | Read | OS perc translumina balloon angioplast stenting coronary art | diagnostic | res67: CVD_Read_Code | |||
| 793Gz00 | Read | Perc translum balloon angioplasty stenting coronary art NOS | diagnostic | res67: CVD_Read_Code | |||
| 793H.00 | Read | Transluminal operations on cardiac conduit | diagnostic | res67: CVD_Read_Code | |||
| 793H000 | Read | Percutaneous transluminal balloon dilation cardiac conduit | diagnostic | res67: CVD_Read_Code | |||
| 7A54500 | Read | Rotary blade angioplasty | diagnostic | res67: CVD_Read_Code | |||
| 7A6G100 | Read | Peroperative angioplasty | diagnostic | res67: CVD_Read_Code | |||
| 7A6H300 | Read | Prosthetic graft patch angioplasty | diagnostic | res67: CVD_Read_Code | |||
| 7A6H400 | Read | Percutaneous transluminal angioplasty of vascular graft | diagnostic | res67: CVD_Read_Code | |||
| 7P24200 | Read | Delivery of rehabilitation for stroke | diagnostic | res67: CVD_Read_Code | |||
| 8CRB.00 | Read | Transient ischaemic attack clinical management plan | diagnostic | res67: CVD_Read_Code | |||
| 8HBJ.00 | Read | Stroke / transient ischaemic attack referral | diagnostic | res67: CVD_Read_Code | |||
| 8HHM.00 | Read | Ref to multidisciplinary stroke function improvement service | diagnostic | res67: CVD_Read_Code | |||
| 8HTQ.00 | Read | Referral to stroke clinic | diagnostic | res67: CVD_Read_Code | |||
| 9N0p.00 | Read | Seen in stroke clinic | diagnostic | res67: CVD_Read_Code | |||
| 9N4X.00 | Read | DNA - Did not attend stroke clinic | diagnostic | res67: CVD_Read_Code | |||
| F423600 | Read | Amaurosis fugax | diagnostic | res67: CVD_Read_Code | |||
| G30..00 | Read | Acute myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G300.00 | Read | Acute anterolateral infarction | diagnostic | res67: CVD_Read_Code | |||
| G301.00 | Read | Other specified anterior myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G301000 | Read | Acute anteroapical infarction | diagnostic | res67: CVD_Read_Code | |||
| G30..11 | Read | Attack - heart | diagnostic | res67: CVD_Read_Code | |||
| G301100 | Read | Acute anteroseptal infarction | diagnostic | res67: CVD_Read_Code | |||
| G30..12 | Read | Coronary thrombosis | diagnostic | res67: CVD_Read_Code | |||
| G30..13 | Read | Cardiac rupture following myocardial infarction (MI) | diagnostic | res67: CVD_Read_Code | |||
| G30..14 | Read | Heart attack | diagnostic | res67: CVD_Read_Code | |||
| G30..15 | Read | MI - acute myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G30..16 | Read | Thrombosis - coronary | diagnostic | res67: CVD_Read_Code | |||
| G30..17 | Read | Silent myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G301z00 | Read | Anterior myocardial infarction NOS | diagnostic | res67: CVD_Read_Code | |||
| G302.00 | Read | Acute inferolateral infarction | diagnostic | res67: CVD_Read_Code | |||
| G303.00 | Read | Acute inferoposterior infarction | diagnostic | res67: CVD_Read_Code | |||
| G304.00 | Read | Posterior myocardial infarction NOS | diagnostic | res67: CVD_Read_Code | |||
| G305.00 | Read | Lateral myocardial infarction NOS | diagnostic | res67: CVD_Read_Code | |||
| G306.00 | Read | True posterior myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G307.00 | Read | Acute subendocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G307000 | Read | Acute non-Q wave infarction | diagnostic | res67: CVD_Read_Code | |||
| G307100 | Read | Acute non-ST segment elevation myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G308.00 | Read | Inferior myocardial infarction NOS | diagnostic | res67: CVD_Read_Code | |||
| G309.00 | Read | Acute Q-wave infarct | diagnostic | res67: CVD_Read_Code | |||
| G30A.00 | Read | Mural thrombosis | diagnostic | res67: CVD_Read_Code | |||
| G30B.00 | Read | Acute posterolateral myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G30X.00 | Read | Acute transmural myocardial infarction of unspecif site | diagnostic | res67: CVD_Read_Code | |||
| G30X000 | Read | Acute ST segment elevation myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G30y.00 | Read | Other acute myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G30y000 | Read | Acute atrial infarction | diagnostic | res67: CVD_Read_Code | |||
| G30y100 | Read | Acute papillary muscle infarction | diagnostic | res67: CVD_Read_Code | |||
| G30y200 | Read | Acute septal infarction | diagnostic | res67: CVD_Read_Code | |||
| G30yz00 | Read | Other acute myocardial infarction NOS | diagnostic | res67: CVD_Read_Code | |||
| G30z.00 | Read | Acute myocardial infarction NOS | diagnostic | res67: CVD_Read_Code | |||
| G31..00 | Read | Other acute and subacute ischaemic heart disease | diagnostic | res67: CVD_Read_Code | |||
| G310.00 | Read | Postmyocardial infarction syndrome | diagnostic | res67: CVD_Read_Code | |||
| G310.11 | Read | Dressler's syndrome | diagnostic | res67: CVD_Read_Code | |||
| G311.00 | Read | Preinfarction syndrome | diagnostic | res67: CVD_Read_Code | |||
| G311100 | Read | Unstable angina | diagnostic | res67: CVD_Read_Code | |||
| G311.11 | Read | Crescendo angina | diagnostic | res67: CVD_Read_Code | |||
| G311.12 | Read | Impending infarction | diagnostic | res67: CVD_Read_Code | |||
| G311.13 | Read | Unstable angina | diagnostic | res67: CVD_Read_Code | |||
| G311.14 | Read | Angina at rest | diagnostic | res67: CVD_Read_Code | |||
| G311200 | Read | Angina at rest | diagnostic | res67: CVD_Read_Code | |||
| G311300 | Read | Refractory angina | diagnostic | res67: CVD_Read_Code | |||
| G311400 | Read | Worsening angina | diagnostic | res67: CVD_Read_Code | |||
| G311500 | Read | Acute coronary syndrome | diagnostic | res67: CVD_Read_Code | |||
| G311z00 | Read | Preinfarction syndrome NOS | diagnostic | res67: CVD_Read_Code | |||
| G312.00 | Read | Coronary thrombosis not resulting in myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G31y.00 | Read | Other acute and subacute ischaemic heart disease | diagnostic | res67: CVD_Read_Code | |||
| G31y000 | Read | Acute coronary insufficiency | diagnostic | res67: CVD_Read_Code | |||
| G31y100 | Read | Microinfarction of heart | diagnostic | res67: CVD_Read_Code | |||
| G31y200 | Read | Subendocardial ischaemia | diagnostic | res67: CVD_Read_Code | |||
| G31y300 | Read | Transient myocardial ischaemia | diagnostic | res67: CVD_Read_Code | |||
| G31yz00 | Read | Other acute and subacute ischaemic heart disease NOS | diagnostic | res67: CVD_Read_Code | |||
| G32..00 | Read | Old myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G32..11 | Read | Healed myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G32..12 | Read | Personal history of myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G33..00 | Read | Angina pectoris | diagnostic | res67: CVD_Read_Code | |||
| G330.00 | Read | Angina decubitus | diagnostic | res67: CVD_Read_Code | |||
| G330000 | Read | Nocturnal angina | diagnostic | res67: CVD_Read_Code | |||
| G330z00 | Read | Angina decubitus NOS | diagnostic | res67: CVD_Read_Code | |||
| G331.00 | Read | Prinzmetal's angina | diagnostic | res67: CVD_Read_Code | |||
| G331.11 | Read | Variant angina pectoris | diagnostic | res67: CVD_Read_Code | |||
| G332.00 | Read | Coronary artery spasm | diagnostic | res67: CVD_Read_Code | |||
| G33z.00 | Read | Angina pectoris NOS | diagnostic | res67: CVD_Read_Code | |||
| G33z000 | Read | Status anginosus | diagnostic | res67: CVD_Read_Code | |||
| G33z100 | Read | Stenocardia | diagnostic | res67: CVD_Read_Code | |||
| G33z200 | Read | Syncope anginosa | diagnostic | res67: CVD_Read_Code | |||
| G33z300 | Read | Angina on effort | diagnostic | res67: CVD_Read_Code | |||
| G33z500 | Read | Post infarct angina | diagnostic | res67: CVD_Read_Code | |||
| G33z600 | Read | New onset angina | diagnostic | res67: CVD_Read_Code | |||
| G33z700 | Read | Stable angina | diagnostic | res67: CVD_Read_Code | |||
| G33zz00 | Read | Angina pectoris NOS | diagnostic | res67: CVD_Read_Code | |||
| G344.00 | Read | Silent myocardial ischaemia | diagnostic | res67: CVD_Read_Code | |||
| G34y.00 | Read | Other specified chronic ischaemic heart disease | diagnostic | res67: CVD_Read_Code | |||
| G34y000 | Read | Chronic coronary insufficiency | diagnostic | res67: CVD_Read_Code | |||
| G34y100 | Read | Chronic myocardial ischaemia | diagnostic | res67: CVD_Read_Code | |||
| G34yz00 | Read | Other specified chronic ischaemic heart disease NOS | diagnostic | res67: CVD_Read_Code | |||
| G34z.00 | Read | Other chronic ischaemic heart disease NOS | diagnostic | res67: CVD_Read_Code | |||
| G35..00 | Read | Subsequent myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G350.00 | Read | Subsequent myocardial infarction of anterior wall | diagnostic | res67: CVD_Read_Code | |||
| G351.00 | Read | Subsequent myocardial infarction of inferior wall | diagnostic | res67: CVD_Read_Code | |||
| G353.00 | Read | Subsequent myocardial infarction of other sites | diagnostic | res67: CVD_Read_Code | |||
| G35X.00 | Read | Subsequent myocardial infarction of unspecified site | diagnostic | res67: CVD_Read_Code | |||
| G36..00 | Read | Certain current complication follow acute myocardial infarct | diagnostic | res67: CVD_Read_Code | |||
| G360.00 | Read | Haemopericardium/current comp folow acut myocard infarct | diagnostic | res67: CVD_Read_Code | |||
| G361.00 | Read | Atrial septal defect/curr comp folow acut myocardal infarct | diagnostic | res67: CVD_Read_Code | |||
| G362.00 | Read | Ventric septal defect/curr comp fol acut myocardal infarctn | diagnostic | res67: CVD_Read_Code | |||
| G363.00 | Read | Ruptur cardiac wall w'out haemopericard/cur comp fol ac MI | diagnostic | res67: CVD_Read_Code | |||
| G364.00 | Read | Ruptur chordae tendinae/curr comp fol acute myocard infarct | diagnostic | res67: CVD_Read_Code | |||
| G365.00 | Read | Rupture papillary muscle/curr comp fol acute myocard infarct | diagnostic | res67: CVD_Read_Code | |||
| G366.00 | Read | Thrombosis atrium,auric append&vent/curr comp foll acute MI | diagnostic | res67: CVD_Read_Code | |||
| G38..00 | Read | Postoperative myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G380.00 | Read | Postoperative transmural myocardial infarction anterior wall | diagnostic | res67: CVD_Read_Code | |||
| G381.00 | Read | Postoperative transmural myocardial infarction inferior wall | diagnostic | res67: CVD_Read_Code | |||
| G382.00 | Read | Postoperative transmural myocardial infarction other sites | diagnostic | res67: CVD_Read_Code | |||
| G383.00 | Read | Postoperative transmural myocardial infarction unspec site | diagnostic | res67: CVD_Read_Code | |||
| G384.00 | Read | Postoperative subendocardial myocardial infarction | diagnostic | res67: CVD_Read_Code | |||
| G38z.00 | Read | Postoperative myocardial infarction, unspecified | diagnostic | res67: CVD_Read_Code | |||
| G501.00 | Read | Post infarction pericarditis | diagnostic | res67: CVD_Read_Code | |||
| G6...00 | Read | Cerebrovascular disease | diagnostic | res67: CVD_Read_Code | |||
| G61..00 | Read | Intracerebral haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G610.00 | Read | Cortical haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G611.00 | Read | Internal capsule haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G61..11 | Read | CVA - cerebrovascular accid due to intracerebral haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G61..12 | Read | Stroke due to intracerebral haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G612.00 | Read | Basal nucleus haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G613.00 | Read | Cerebellar haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G614.00 | Read | Pontine haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G615.00 | Read | Bulbar haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G616.00 | Read | External capsule haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G617.00 | Read | Intracerebral haemorrhage, intraventricular | diagnostic | res67: CVD_Read_Code | |||
| G618.00 | Read | Intracerebral haemorrhage, multiple localized | diagnostic | res67: CVD_Read_Code | |||
| G61X.00 | Read | Intracerebral haemorrhage in hemisphere, unspecified | diagnostic | res67: CVD_Read_Code | |||
| G61X000 | Read | Left sided intracerebral haemorrhage, unspecified | diagnostic | res67: CVD_Read_Code | |||
| G61X100 | Read | Right sided intracerebral haemorrhage, unspecified | diagnostic | res67: CVD_Read_Code | |||
| G61z.00 | Read | Intracerebral haemorrhage NOS | diagnostic | res67: CVD_Read_Code | |||
| G63..00 | Read | Precerebral arterial occlusion | diagnostic | res67: CVD_Read_Code | |||
| G630.00 | Read | Basilar artery occlusion | diagnostic | res67: CVD_Read_Code | |||
| G631.00 | Read | Carotid artery occlusion | diagnostic | res67: CVD_Read_Code | |||
| G63..11 | Read | Infarction - precerebral | diagnostic | res67: CVD_Read_Code | |||
| G631.12 | Read | Thrombosis, carotid artery | diagnostic | res67: CVD_Read_Code | |||
| G632.00 | Read | Vertebral artery occlusion | diagnostic | res67: CVD_Read_Code | |||
| G633.00 | Read | Multiple and bilateral precerebral arterial occlusion | diagnostic | res67: CVD_Read_Code | |||
| G63y.00 | Read | Other precerebral artery occlusion | diagnostic | res67: CVD_Read_Code | |||
| G63y000 | Read | Cerebral infarct due to thrombosis of precerebral arteries | diagnostic | res67: CVD_Read_Code | |||
| G63y100 | Read | Cerebral infarction due to embolism of precerebral arteries | diagnostic | res67: CVD_Read_Code | |||
| G63z.00 | Read | Precerebral artery occlusion NOS | diagnostic | res67: CVD_Read_Code | |||
| G64..00 | Read | Cerebral arterial occlusion | diagnostic | res67: CVD_Read_Code | |||
| G640.00 | Read | Cerebral thrombosis | diagnostic | res67: CVD_Read_Code | |||
| G640000 | Read | Cerebral infarction due to thrombosis of cerebral arteries | diagnostic | res67: CVD_Read_Code | |||
| G641.00 | Read | Cerebral embolism | diagnostic | res67: CVD_Read_Code | |||
| G641000 | Read | Cerebral infarction due to embolism of cerebral arteries | diagnostic | res67: CVD_Read_Code | |||
| G64..11 | Read | CVA - cerebral artery occlusion | diagnostic | res67: CVD_Read_Code | |||
| G641.11 | Read | Cerebral embolus | diagnostic | res67: CVD_Read_Code | |||
| G64..12 | Read | Infarction - cerebral | diagnostic | res67: CVD_Read_Code | |||
| G64..13 | Read | Stroke due to cerebral arterial occlusion | diagnostic | res67: CVD_Read_Code | |||
| G64z.00 | Read | Cerebral infarction NOS | diagnostic | res67: CVD_Read_Code | |||
| G64z000 | Read | Brainstem infarction | diagnostic | res67: CVD_Read_Code | |||
| G64z100 | Read | Wallenberg syndrome | diagnostic | res67: CVD_Read_Code | |||
| G64z.11 | Read | Brainstem infarction NOS | diagnostic | res67: CVD_Read_Code | |||
| G64z111 | Read | Lateral medullary syndrome | diagnostic | res67: CVD_Read_Code | |||
| G64z.12 | Read | Cerebellar infarction | diagnostic | res67: CVD_Read_Code | |||
| G64z200 | Read | Left sided cerebral infarction | diagnostic | res67: CVD_Read_Code | |||
| G64z300 | Read | Right sided cerebral infarction | diagnostic | res67: CVD_Read_Code | |||
| G64z400 | Read | Infarction of basal ganglia | diagnostic | res67: CVD_Read_Code | |||
| G65..00 | Read | Transient cerebral ischaemia | diagnostic | res67: CVD_Read_Code | |||
| G651.00 | Read | Vertebral artery syndrome | diagnostic | res67: CVD_Read_Code | |||
| G65..12 | Read | Transient ischaemic attack | diagnostic | res67: CVD_Read_Code | |||
| G652.00 | Read | Subclavian steal syndrome | diagnostic | res67: CVD_Read_Code | |||
| G653.00 | Read | Carotid artery syndrome hemispheric | diagnostic | res67: CVD_Read_Code | |||
| G654.00 | Read | Multiple and bilateral precerebral artery syndromes | diagnostic | res67: CVD_Read_Code | |||
| G65y.00 | Read | Other transient cerebral ischaemia | diagnostic | res67: CVD_Read_Code | |||
| G65z.00 | Read | Transient cerebral ischaemia NOS | diagnostic | res67: CVD_Read_Code | |||
| G65z100 | Read | Intermittent cerebral ischaemia | diagnostic | res67: CVD_Read_Code | |||
| G65zz00 | Read | Transient cerebral ischaemia NOS | diagnostic | res67: CVD_Read_Code | |||
| G66..00 | Read | Stroke and cerebrovascular accident unspecified | diagnostic | res67: CVD_Read_Code | |||
| G660.00 | Read | Middle cerebral artery syndrome | diagnostic | res67: CVD_Read_Code | |||
| G66..11 | Read | CVA unspecified | diagnostic | res67: CVD_Read_Code | |||
| G66..12 | Read | Stroke unspecified | diagnostic | res67: CVD_Read_Code | |||
| G66..13 | Read | CVA - Cerebrovascular accident unspecified | diagnostic | res67: CVD_Read_Code | |||
| G663.00 | Read | Brain stem stroke syndrome | diagnostic | res67: CVD_Read_Code | |||
| G664.00 | Read | Cerebellar stroke syndrome | diagnostic | res67: CVD_Read_Code | |||
| G665.00 | Read | Pure motor lacunar syndrome | diagnostic | res67: CVD_Read_Code | |||
| G666.00 | Read | Pure sensory lacunar syndrome | diagnostic | res67: CVD_Read_Code | |||
| G667.00 | Read | Left sided CVA | diagnostic | res67: CVD_Read_Code | |||
| G668.00 | Read | Right sided CVA | diagnostic | res67: CVD_Read_Code | |||
| G676000 | Read | Cereb infarct due cerebral venous thrombosis, nonpyogenic | diagnostic | res67: CVD_Read_Code | |||
| G677000 | Read | Occlusion and stenosis of middle cerebral artery | diagnostic | res67: CVD_Read_Code | |||
| G677100 | Read | Occlusion and stenosis of anterior cerebral artery | diagnostic | res67: CVD_Read_Code | |||
| G677200 | Read | Occlusion and stenosis of posterior cerebral artery | diagnostic | res67: CVD_Read_Code | |||
| G677300 | Read | Occlusion and stenosis of cerebellar arteries | diagnostic | res67: CVD_Read_Code | |||
| G677400 | Read | Occlusion+stenosis of multiple and bilat cerebral arteries | diagnostic | res67: CVD_Read_Code | |||
| G681.00 | Read | Sequelae of intracerebral haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G682.00 | Read | Sequelae of other nontraumatic intracranial haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| G683.00 | Read | Sequelae of cerebral infarction | diagnostic | res67: CVD_Read_Code | |||
| G68W.00 | Read | Sequelae/other + unspecified cerebrovascular diseases | diagnostic | res67: CVD_Read_Code | |||
| G6W..00 | Read | Cereb infarct due unsp occlus/stenos precerebr arteries | diagnostic | res67: CVD_Read_Code | |||
| Gyu3000 | Read | [X]Other forms of angina pectoris | diagnostic | res67: CVD_Read_Code | |||
| Gyu3100 | Read | [X]Other current complicatns following acute myocard infarct | diagnostic | res67: CVD_Read_Code | |||
| Gyu3300 | Read | [X]Other forms of chronic ischaemic heart disease | diagnostic | res67: CVD_Read_Code | |||
| Gyu3400 | Read | [X]Acute transmural myocardial infarction of unspecif site | diagnostic | res67: CVD_Read_Code | |||
| Gyu3500 | Read | [X]Subsequent myocardial infarction of other sites | diagnostic | res67: CVD_Read_Code | |||
| Gyu3600 | Read | [X]Subsequent myocardial infarction of unspecified site | diagnostic | res67: CVD_Read_Code | |||
| Gyu6200 | Read | [X]Other intracerebral haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| Gyu6300 | Read | [X]Cerebrl infarctn due/unspcf occlusn or sten/cerebrl artrs | diagnostic | res67: CVD_Read_Code | |||
| Gyu6400 | Read | [X]Other cerebral infarction | diagnostic | res67: CVD_Read_Code | |||
| Gyu6500 | Read | [X]Occlusion and stenosis of other precerebral arteries | diagnostic | res67: CVD_Read_Code | |||
| Gyu6600 | Read | [X]Occlusion and stenosis of other cerebral arteries | diagnostic | res67: CVD_Read_Code | |||
| Gyu6B00 | Read | [X]Sequelae of other nontraumatic intracranial haemorrhage | diagnostic | res67: CVD_Read_Code | |||
| Gyu6C00 | Read | [X]Sequelae of stroke,not specfd as h'morrhage or infarction | diagnostic | res67: CVD_Read_Code | |||
| Gyu6D00 | Read | [X]Sequelae/other + unspecified cerebrovascular diseases | diagnostic | res67: CVD_Read_Code | |||
| Gyu6F00 | Read | [X]Intracerebral haemorrhage in hemisphere, unspecified | diagnostic | res67: CVD_Read_Code | |||
| Gyu6G00 | Read | [X]Cereb infarct due unsp occlus/stenos precerebr arteries | diagnostic | res67: CVD_Read_Code | |||
| SP07600 | Read | Coronary artery bypass graft occlusion | diagnostic | res67: CVD_Read_Code | |||
| ZLEP.00 | Read | Discharge from stroke serv | diagnostic | res67: CVD_Read_Code | |||
| ZV12511 | Read | [V]Personal history of stroke | diagnostic | res67: CVD_Read_Code | |||
| ZV45700 | Read | [V]Presence of aortocoronary bypass graft | diagnostic | res67: CVD_Read_Code | |||
| ZV45800 | Read | [V]Presence of coronary angioplasty implant and graft | diagnostic | res67: CVD_Read_Code | |||
| ZV45K00 | Read | [V]Presence of coronary artery bypass graft | diagnostic | res67: CVD_Read_Code | |||
| ZV45K11 | Read | [V]Presence of coronary artery bypass graft - CABG | diagnostic | res67: CVD_Read_Code | |||
| ZV45L00 | Read | [V]Status following coronary angioplasty NOS | diagnostic | res67: CVD_Read_Code |
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Code list links:
ClinicalCodes is a project at the University of Manchester Institute of Population Health
The ClinicalCodes project is funded by the National Institute for Health Research (NIHR) School for Primary Care Research (SPCR)