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Research article:

Cardiovascular Risk and Risk Factor Management in Type 2 Diabetes: A Population-Based Cohort Study Assessing Sex Disparities

Reference:

Alison K. Wright, Evangelos Kontopantelis, Richard Emsley, Iain Edward Buchan, Mamas A. Mamas, Naveed Sattar, Darren M. Ashcroft, and Martin K. Rutter(2019) Cardiovascular Risk and Risk Factor Management in Type 2 Diabetes: A Population-Based Cohort Study Assessing Sex Disparities. Circulation, doi: 10.1161/CIRCULATIONAHA.118.039100

Link to article
Abstract
Background: With recent changes in UK clinical practice for diabetes care, contemporary estimates of sex disparities in cardiovascular risk and risk factor management are needed. Methods: In this retrospective cohort study, using the Clinical Practice Research Datalink linked to hospital and death records for people in England, we identified 79,985 patients with incident T2DM between 2006-2013 matched to 386,547 patients without diabetes. Sex-stratified Cox models were used to assess cardiovascular risk. Results: Compared to women without T2DM, women with T2DM had a higher cardiovascular event risk (adjusted HR 1.20 [95% CI 1.12-1.28]) with similar corresponding data in men (HR 1.12 [1.06-1.19]) leading to a non-significant higher relative risk in women (risk ratio 1.07 [0.98-1.17]). However, some important sex differences in the management of risk factors were observed. Compared to men with T2DM, women with T2DM were more likely to be obese, hypertensive and have hypercholesterolaemia but were less likely to be prescribed lipid-lowering medication and ACE inhibitors, especially if they had CVD. Conclusions: Compared to men developing T2DM, women with T2DM do not have a significantly higher relative increase in cardiovascular risk, but ongoing sex disparities in prescribing should prompt heightened efforts to improve the standard and equity of diabetes care in women and men.
Author for correspondence
Alison Wright
Email for correspondence
alison.wright@manchester.ac.uk

Code list: res72: Hormone replacement therapy

194 codes in list

Code Coding system Description Entity type List name
10052 CPRD_product_code PROGYNOVA TS 50 patch 50mcg/24hours (3.8 mg/unit) [BAYER] drug res72: Hormone replacement therapy
10076 CPRD_product_code ESTRADOT patch 75 micrograms/24 hours (1.17mg/unit) [NOVARTIS] drug res72: Hormone replacement therapy
10096 CPRD_product_code ESTRADOT patch 100 micrograms/24 hours (1.56mg/unit) [NOVARTIS] drug res72: Hormone replacement therapy
10126 CPRD_product_code ESTRADOT patch 25 micrograms/24 hours (0.39mg/unit) [NOVARTIS] drug res72: Hormone replacement therapy
1014 CPRD_product_code ESTRAPAK 50 patch and tablets 50mcg/24hours(4mg/unit) + 1mg [NOV/CIBA] drug res72: Hormone replacement therapy
10180 CPRD_product_code ESTRADOT patch 50 micrograms/24 hours (0.78mg/unit) [NOVARTIS] drug res72: Hormone replacement therapy
10593 CPRD_product_code estriol tablets 1mg drug res72: Hormone replacement therapy
10946 CPRD_product_code MENOREST patch 50micrograms/24 hours (4.33mg/unit) [NOVARTIS] drug res72: Hormone replacement therapy
10967 CPRD_product_code MENOREST patch 37.5micrograms/24 hours (3.29mg/unit) [NOVARTIS] drug res72: Hormone replacement therapy
11157 CPRD_product_code estradiol and (estradiol with dydrogesterone) tablets 1mg + (1mg + 10mg) drug res72: Hormone replacement therapy
11363 CPRD_product_code estradiol and (estradiol with dydrogesterone) tablets 2mg + (2mg + 20mg) drug res72: Hormone replacement therapy
11375 CPRD_product_code estradiol once weekly patch 50micrograms/24 hours(1.5mg/unit) drug res72: Hormone replacement therapy
11430 CPRD_product_code estradiol once weekly patch 25micrograms/24 hours drug res72: Hormone replacement therapy
11511 CPRD_product_code estradiol and (estradiol with dydrogesterone) tablets 2mg + (2mg + 10 mg) drug res72: Hormone replacement therapy
11672 CPRD_product_code estradiol twice weekly patch 25micrograms/24 hours (0.75mg/unit) drug res72: Hormone replacement therapy
1183 CPRD_product_code ESTRACOMBI TTS patch [NOV/CIBA] drug res72: Hormone replacement therapy
11882 CPRD_product_code estradiol twice weekly patch 50 micrograms/24 hours (0.78mg/unit) drug res72: Hormone replacement therapy
1268 CPRD_product_code KLIOFEM tablets 2mg + 1mg [NOVO] drug res72: Hormone replacement therapy
12713 CPRD_product_code estradiol valerate and (estradiol valerate with norethisterone) tablets 2mg + (2mg + 1 mg) drug res72: Hormone replacement therapy
12773 CPRD_product_code estradiol twice weekly patch 100micrograms/24hrs (3.0mg/unit) drug res72: Hormone replacement therapy
12788 CPRD_product_code estradiol with norethisterone acetate (continuous combined) tablets 1mg + 0.5mg drug res72: Hormone replacement therapy
12807 CPRD_product_code estradiol with norethisterone acetate (continuous combined) tablets 2mg + 0.7mg drug res72: Hormone replacement therapy
12907 CPRD_product_code estradiol and (estradiol with dydrogesterone) tablets 1mg + 5mg drug res72: Hormone replacement therapy
12953 CPRD_product_code estradiol with dydrogesterone tablets 1mg + 5mg drug res72: Hormone replacement therapy
13146 CPRD_product_code NOVOFEM tablets 1mg + (1mg + 1mg) [NOVO] drug res72: Hormone replacement therapy
13582 CPRD_product_code MENOREST patch 75micrograms/24hours (6.57mg/unit) [NOVARTIS] drug res72: Hormone replacement therapy
13990 CPRD_product_code estradiol with norethisterone acetate patch and tablets 50mcg/24hours(4mg/unit) + 1mg drug res72: Hormone replacement therapy
14027 CPRD_product_code estradiol with (estradiol + norethisterone acetate) tablets 1mg + (1mg + 1mg) drug res72: Hormone replacement therapy
14234 CPRD_product_code estradiol twice weekly patch 37.5micrograms/24 hours drug res72: Hormone replacement therapy
14569 CPRD_product_code estradiol and (estradiol with norethisterone) and (estradiol) triphasic tablets 2mg + (2mg + 1mg) + drug res72: Hormone replacement therapy
14580 CPRD_product_code DERMESTRIL patch 25micrograms/24 hours (2mg/unit) [STRAKAN] drug res72: Hormone replacement therapy
14596 CPRD_product_code estradiol and (estradiol with norethisterone) and (estradiol) triphasic forte tablets 4mg + (4mg + 1 drug res72: Hormone replacement therapy
14792 CPRD_product_code estradiol twice weekly patch 50micrograms/24 hours(1.5mg/unit) drug res72: Hormone replacement therapy
14812 CPRD_product_code estradiol with (estradiol + norethisterone acetate) twice weekly patch 50mcg/24 hr + (50mcg+170mcg/2 drug res72: Hormone replacement therapy
1488 CPRD_product_code EVOREL -50 patch 50mcg/24 hours (3.2mg/unit) [JANSSEN] drug res72: Hormone replacement therapy
1489 CPRD_product_code EVOREL -75 patch 75micrograms/24 hours(4.8mg/unit) [JANSSEN] drug res72: Hormone replacement therapy
14950 CPRD_product_code estradiol with norethisterone acetate twice weekly patch (50mcg + 170mcg)/24 hr drug res72: Hormone replacement therapy
15100 CPRD_product_code estradiol twice weekly patch 37.5micrograms/24 hours (3.29mg/unit) drug res72: Hormone replacement therapy
15194 CPRD_product_code DERMESTRIL patch 100micrograms/24 hours (8mg/unit) [STRAKAN] drug res72: Hormone replacement therapy
15298 CPRD_product_code estradiol twice weekly patch 25 micrograms/24 hours (0.39mg/unit) drug res72: Hormone replacement therapy
15328 CPRD_product_code estradiol twice weekly patch 25micrograms/24 hours drug res72: Hormone replacement therapy
15869 CPRD_product_code DERMESTRIL patch 50micrograms/24 hours (4mg/unit) [STRAKAN] drug res72: Hormone replacement therapy
15880 CPRD_product_code DERMESTRIL SEPTEM patch 75micrograms/24 hours [STRAKAN] drug res72: Hormone replacement therapy
16437 CPRD_product_code estradiol once weekly patch 100mcg/24 hour (7.6mg/unit) drug res72: Hormone replacement therapy
16443 CPRD_product_code FEMTAB CONTINUOUS tablets 2mg + 1mg [MERCK PHAR] drug res72: Hormone replacement therapy
16997 CPRD_product_code estradiol with (estradiol + norethisterone acetate) tablets 2mg + (2mg + 1 mg) drug res72: Hormone replacement therapy
17475 CPRD_product_code ADGYN COMBI tablets 2mg + (2mg + 1mg) [STRAKAN] drug res72: Hormone replacement therapy
18009 CPRD_product_code estradiol once weekly patch 50mcg/24hours (3.8 mg/unit) drug res72: Hormone replacement therapy
18218 CPRD_product_code estradiol twice weekly patch 100micrograms/24 hours drug res72: Hormone replacement therapy
18311 CPRD_product_code estriol tablets 250micrograms drug res72: Hormone replacement therapy
18383 CPRD_product_code estradiol twice weekly patch 80micrograms/24 hours drug res72: Hormone replacement therapy
18437 CPRD_product_code estradiol twice weekly patch 75micrograms/24hours (6.57mg/unit) drug res72: Hormone replacement therapy
18502 CPRD_product_code estradiol twice weekly patch 75micrograms/24 hours (2.25mg/unit) drug res72: Hormone replacement therapy
18600 CPRD_product_code estradiol twice weekly patch 75micrograms/24 hours drug res72: Hormone replacement therapy
1873 CPRD_product_code CLIMAVAL tablets 1mg [NOV/SANDOZ] drug res72: Hormone replacement therapy
18901 CPRD_product_code estradiol twice weekly patch 50micrograms/24 hours drug res72: Hormone replacement therapy
19135 CPRD_product_code ESTRADIOL implant 50mg [ORGANON] drug res72: Hormone replacement therapy
19145 CPRD_product_code estradiol twice weekly patch 50micrograms/24 hours (4.33mg/unit) drug res72: Hormone replacement therapy
1922 CPRD_product_code HORMONIN tablets [SHIRE] drug res72: Hormone replacement therapy
19487 CPRD_product_code ESTRADOT patch 37.5micrograms/24hours (0.585mg/unit) [NOVARTIS] drug res72: Hormone replacement therapy
20135 CPRD_product_code estradiol twice weekly patch 75 micrograms/24 hours (1.17mg/unit) drug res72: Hormone replacement therapy
20155 CPRD_product_code estradiol once weekly patch 50micrograms/24 hours drug res72: Hormone replacement therapy
206 CPRD_product_code ESTRADERM TTS patch 100micrograms/24 hours (8mg/unit) [NOV/CIBA] drug res72: Hormone replacement therapy
20888 CPRD_product_code ADGYN ESTRO tablets 2mg [STRAKAN] drug res72: Hormone replacement therapy
20895 CPRD_product_code DERMESTRIL SEPTEM patch 50micrograms/24 hours [STRAKAN] drug res72: Hormone replacement therapy
2111 CPRD_product_code CLIMAGEST tablets 2mg [NOV/SANDOZ] drug res72: Hormone replacement therapy
2115 CPRD_product_code KLIOVANCE tablets 1mg + 0.5mg [NOVO] drug res72: Hormone replacement therapy
2140 CPRD_product_code FEMSEVEN 50 patch 50micrograms/24 hours(1.5mg/unit) [MERCK SER] drug res72: Hormone replacement therapy
2141 CPRD_product_code EVOREL -25 patch 25mcg/24 hours (1.6mg/unit) [JANSSEN] drug res72: Hormone replacement therapy
21757 CPRD_product_code ESTRADIOL implant 100mg [ORGANON] drug res72: Hormone replacement therapy
2208 CPRD_product_code TRISEQUENS tablets [NOVO] drug res72: Hormone replacement therapy
22335 CPRD_product_code estradiol once weekly patch 100mcg/24 hours (3.0mg/unit) drug res72: Hormone replacement therapy
2262 CPRD_product_code CLIMAVAL tablets 2mg [NOV/SANDOZ] drug res72: Hormone replacement therapy
2397 CPRD_product_code EVOREL -100 patch 100mcg/24 hours (6.4mg/unit) [JANSSEN] drug res72: Hormone replacement therapy
2452 CPRD_product_code TRISEQUENS forte tablets [NOVO] drug res72: Hormone replacement therapy
2457 CPRD_product_code estradiol valerate tablets 1mg drug res72: Hormone replacement therapy
24764 CPRD_product_code estradiol and (estradiol with norethisterone) tablets 2mg + (2mg + 1mg) drug res72: Hormone replacement therapy
24917 CPRD_product_code estradiol valerate with norethisterone (continuous combined) tablets 2mg + 0.7mg drug res72: Hormone replacement therapy
26049 CPRD_product_code estradiol twice weekly patch 100 micrograms/24 hours (1.56mg/unit) drug res72: Hormone replacement therapy
2728 CPRD_product_code EVOREL PAK treatment pack 50mcg/24hours(3.2mg/unit) + 1mg [JANSSEN] drug res72: Hormone replacement therapy
2729 CPRD_product_code EVOREL CONTI patch (50mcg + 170mcg)/24 hr [JANSSEN] drug res72: Hormone replacement therapy
2766 CPRD_product_code CLIMESSE tablets 2mg + 0.7mg [NOV/SANDOZ] drug res72: Hormone replacement therapy
28230 CPRD_product_code CLINORETTE tablets 2mg [RESOURCE] drug res72: Hormone replacement therapy
29449 CPRD_product_code estradiol injection 1mg/ml drug res72: Hormone replacement therapy
2977 CPRD_product_code estradiol implant 50mg drug res72: Hormone replacement therapy
3002 CPRD_product_code ELLESTE-DUET tablets 1mg [MEDA] drug res72: Hormone replacement therapy
3040 CPRD_product_code ESTRADERM MX patch 50micrograms/24 hours(1.5mg/unit) [NOV/CIBA] drug res72: Hormone replacement therapy
31330 CPRD_product_code estradiol injection 5mg/ml drug res72: Hormone replacement therapy
3179 CPRD_product_code PROGYNOVA tablets 1mg [BAYER] drug res72: Hormone replacement therapy
32930 CPRD_product_code DERMESTRIL SEPTEM patch 25micrograms/24 hours [STRAKAN] drug res72: Hormone replacement therapy
3387 CPRD_product_code ESTRADERM MX patch 25micrograms/24 hours (0.75mg/unit) [NOV/CIBA] drug res72: Hormone replacement therapy
3530 CPRD_product_code FEMOSTON tablets 1mg + 10mg [ABBOTT] drug res72: Hormone replacement therapy
3553 CPRD_product_code FEMOSTON tablets 2mg + 10mg [ABBOTT] drug res72: Hormone replacement therapy
35742 CPRD_product_code estradiol once weekly patch 100micrograms/24 hours drug res72: Hormone replacement therapy
35958 CPRD_product_code BEDOL tablets 2mg [RESOURCE] drug res72: Hormone replacement therapy
37033 CPRD_product_code estradiol transdermal patch 75micrograms/24 hours drug res72: Hormone replacement therapy
37037 CPRD_product_code estradiol transdermal patch 100micrograms/24 hours drug res72: Hormone replacement therapy
37692 CPRD_product_code estradiol transdermal patch 25micrograms/24 hours drug res72: Hormone replacement therapy
37697 CPRD_product_code estradiol transdermal patch 50micrograms/24 hours drug res72: Hormone replacement therapy
38932 CPRD_product_code EVOREL 50 patch [JANSSEN] drug res72: Hormone replacement therapy
38935 CPRD_product_code EVOREL 25 patch [JANSSEN] drug res72: Hormone replacement therapy
38940 CPRD_product_code EVOREL 75 patch [JANSSEN] drug res72: Hormone replacement therapy
38965 CPRD_product_code EVOREL 100 patch [JANSSEN] drug res72: Hormone replacement therapy
390 CPRD_product_code CLIMAGEST tablets 1mg [NOV/SANDOZ] drug res72: Hormone replacement therapy
39622 CPRD_product_code HORMONIN tablets [AMDIPHARM] drug res72: Hormone replacement therapy
41390 CPRD_product_code estradiol with (estradiol + norethisterone acetate) twice weekly patch drug res72: Hormone replacement therapy
4207 CPRD_product_code ELLESTE-DUET tablets 2mg [MEDA] drug res72: Hormone replacement therapy
4244 CPRD_product_code EVOREL SEQUI patch [JANSSEN] drug res72: Hormone replacement therapy
42515 CPRD_product_code estradiol patch 40micrograms/24 hours (1.25mg/unit) drug res72: Hormone replacement therapy
4326 CPRD_product_code PROGYNOVA tablets 2mg [BAYER] drug res72: Hormone replacement therapy
4328 CPRD_product_code ELLESTE-SOLO tablets 1mg [MEDA] drug res72: Hormone replacement therapy
4393 CPRD_product_code ELLESTE-DUET CONTI tablets 2mg + 1mg [MEDA] drug res72: Hormone replacement therapy
44461 CPRD_product_code Estradiol 10microgram pessaries drug res72: Hormone replacement therapy
44494 CPRD_product_code Vagifem 10microgram vaginal tablets (Novo Nordisk Ltd) drug res72: Hormone replacement therapy
4466 CPRD_product_code PROGYNOVA TS patch 50mcg/24hours (3.8 mg/unit) [SCHERING] drug res72: Hormone replacement therapy
4467 CPRD_product_code PROGYNOVA TS forte patch 100mcg/24 hour (7.6mg/unit) [SCHERING] drug res72: Hormone replacement therapy
4511 CPRD_product_code estradiol implant 100mg drug res72: Hormone replacement therapy
4721 CPRD_product_code estradiol twice weekly patch 75micrograms/24 hours(4.8mg/unit) drug res72: Hormone replacement therapy
4882 CPRD_product_code ESTRADERM MX patch 100micrograms/24hrs (3.0mg/unit) [NOV/CIBA] drug res72: Hormone replacement therapy
4909 CPRD_product_code ELLESTE-SOLO tablets 2mg [MEDA] drug res72: Hormone replacement therapy
4956 CPRD_product_code estradiol tablets 1mg drug res72: Hormone replacement therapy
49693 CPRD_product_code Vagifem 25microgram vaginal tablets (Mawdsley-Brooks & Company Ltd) drug res72: Hormone replacement therapy
49694 CPRD_product_code Estraderm TTS 25 patches (DE Pharmaceuticals) drug res72: Hormone replacement therapy
4977 CPRD_product_code ESTRADERM MX patch 75micrograms/24 hours (2.25mg/unit) [NOV/CIBA] drug res72: Hormone replacement therapy
49985 CPRD_product_code Femoston-conti 0.5mg/2.5mg tablets (BGP Products Ltd) drug res72: Hormone replacement therapy
5005 CPRD_product_code estradiol twice weekly patch 50mcg/24 hours (3.2mg/unit) drug res72: Hormone replacement therapy
5012 CPRD_product_code estradiol with norethisterone acetate (continuous combined) tablets 2mg + 1mg drug res72: Hormone replacement therapy
50200 CPRD_product_code Climagest 1mg tablets (Sigma Pharmaceuticals Plc) drug res72: Hormone replacement therapy
5100 CPRD_product_code estradiol twice weekly patch 25mcg/24 hours (1.6mg/unit) drug res72: Hormone replacement therapy
51201 CPRD_product_code Estradot 50micrograms/24hours patches (Necessity Supplies Ltd) drug res72: Hormone replacement therapy
51546 CPRD_product_code Climaval 2mg tablets (Lexon (UK) Ltd) drug res72: Hormone replacement therapy
51688 CPRD_product_code Evorel Conti patches (Lexon (UK) Ltd) drug res72: Hormone replacement therapy
5195 CPRD_product_code FEMOSTON CONTI tablets 1mg + 5mg [ABBOTT] drug res72: Hormone replacement therapy
51978 CPRD_product_code Estraderm MX 25 patches (Stephar (U.K.) Ltd) drug res72: Hormone replacement therapy
52174 CPRD_product_code Estradot 50micrograms/24hours patches (Sigma Pharmaceuticals Plc) drug res72: Hormone replacement therapy
52306 CPRD_product_code Femoston-conti 1mg/5mg tablets (Stephar (U.K.) Ltd) drug res72: Hormone replacement therapy
52441 CPRD_product_code Evorel Conti patches (DE Pharmaceuticals) drug res72: Hormone replacement therapy
52480 CPRD_product_code Estraderm MX 25 patches (Lexon (UK) Ltd) drug res72: Hormone replacement therapy
52632 CPRD_product_code Vagifem 25microgram vaginal tablets (Waymade Healthcare Plc) drug res72: Hormone replacement therapy
52813 CPRD_product_code Nuvelle TS Phase I patches (Bayer Plc) drug res72: Hormone replacement therapy
5292 CPRD_product_code FEMATRIX 40 patch 40micrograms/24 hours (1.25mg/unit) [ABBOTT] drug res72: Hormone replacement therapy
5343 CPRD_product_code estradiol twice weekly patch 25micrograms/24 hours (2mg/unit) drug res72: Hormone replacement therapy
54425 CPRD_product_code Oestrogel Pump-Pack 0.06% gel (DE Pharmaceuticals) drug res72: Hormone replacement therapy
55551 CPRD_product_code Estradiol 500micrograms / Dydrogesterone 2.5mg tablets drug res72: Hormone replacement therapy
56056 CPRD_product_code Generic Elleste Duet 1mg tablets drug res72: Hormone replacement therapy
56081 CPRD_product_code Generic Femoston 1/10mg tablets drug res72: Hormone replacement therapy
56468 CPRD_product_code Oestrogel Pump-Pack 0.06% gel (Waymade Healthcare Plc) drug res72: Hormone replacement therapy
56480 CPRD_product_code Evorel Conti patches (Waymade Healthcare Plc) drug res72: Hormone replacement therapy
57514 CPRD_product_code Estraderm TTS 50 patches (Waymade Healthcare Plc) drug res72: Hormone replacement therapy
57548 CPRD_product_code Oestrogel Pump-Pack 0.06% gel (Sigma Pharmaceuticals Plc) drug res72: Hormone replacement therapy
5755 CPRD_product_code ELLESTE-SOLO MX 40 patch 40micrograms/24 hours (1.25mg/unit) [MEDA] drug res72: Hormone replacement therapy
57562 CPRD_product_code Sandrena 1mg gel sachets (Waymade Healthcare Plc) drug res72: Hormone replacement therapy
5759 CPRD_product_code estradiol twice weekly patch 100micrograms/24 hours (8mg/unit) drug res72: Hormone replacement therapy
57590 CPRD_product_code Progynova TS 50 patches (Dowelhurst Ltd) drug res72: Hormone replacement therapy
58035 CPRD_product_code Generic Elleste Duet 2mg tablets drug res72: Hormone replacement therapy
58516 CPRD_product_code Generic Femoston 2/10mg tablets drug res72: Hormone replacement therapy
58575 CPRD_product_code Generic Climagest 1mg tablets drug res72: Hormone replacement therapy
6030 CPRD_product_code NUVELLE CONTINUOUS tablets 2mg + 1mg [BAYER] drug res72: Hormone replacement therapy
6059 CPRD_product_code estradiol twice weekly patch 100mcg/24 hours (6.4mg/unit) drug res72: Hormone replacement therapy
60637 CPRD_product_code Climaval 1mg tablets (Lexon (UK) Ltd) drug res72: Hormone replacement therapy
6082 CPRD_product_code FEMSEVEN 75 patch 75micrograms/24 hours (2.25mg/unit) [MERCK SER] drug res72: Hormone replacement therapy
6177 CPRD_product_code FEMSEVEN 100 patch 100mcg/24 hours (3.0mg/unit) [MERCK SER] drug res72: Hormone replacement therapy
62530 CPRD_product_code Generic Tridestra tablets drug res72: Hormone replacement therapy
64580 CPRD_product_code Elleste Duet Conti tablets (Mawdsley-Brooks & Company Ltd) drug res72: Hormone replacement therapy
64735 CPRD_product_code Estradot 50micrograms/24hours patches (Waymade Healthcare Plc) drug res72: Hormone replacement therapy
64995 CPRD_product_code Climesse tablets (Lexon (UK) Ltd) drug res72: Hormone replacement therapy
65009 CPRD_product_code Generic Trisequens tablets drug res72: Hormone replacement therapy
6538 CPRD_product_code FEMTAB tablets 2mg [MERCK PHAR] drug res72: Hormone replacement therapy
6563 CPRD_product_code estradiol once weekly patch 75micrograms/24 hours drug res72: Hormone replacement therapy
65810 CPRD_product_code Femoston 2/10mg tablets (Sigma Pharmaceuticals Plc) drug res72: Hormone replacement therapy
6601 CPRD_product_code estradiol twice weekly patch 25micrograms/24 hours (2mg/unit) drug res72: Hormone replacement therapy
6603 CPRD_product_code estradiol with estrone and estriol tablets drug res72: Hormone replacement therapy
6622 CPRD_product_code ZUMENON tablets 2mg [ABBOTT] drug res72: Hormone replacement therapy
66404 CPRD_product_code Climagest 1mg tablets (Waymade Healthcare Plc) drug res72: Hormone replacement therapy
66434 CPRD_product_code Generic Evorel Sequi transdermal patches drug res72: Hormone replacement therapy
66575 CPRD_product_code Evorel 50 patches (Lexon (UK) Ltd) drug res72: Hormone replacement therapy
6793 CPRD_product_code estradiol twice weekly patch 40micrograms/24 hours drug res72: Hormone replacement therapy
7001 CPRD_product_code estradiol valerate tablets 2mg drug res72: Hormone replacement therapy
7251 CPRD_product_code FEMTAB tablets 1mg [MERCK PHAR] drug res72: Hormone replacement therapy
7381 CPRD_product_code estradiol tablets 2mg drug res72: Hormone replacement therapy
7388 CPRD_product_code ZUMENON tablets 1mg [ABBOTT] drug res72: Hormone replacement therapy
8162 CPRD_product_code estradiol with norethisterone patch and tablets 50mcg/24hours(3.2mg/unit) + 1mg drug res72: Hormone replacement therapy
8465 CPRD_product_code OVESTIN tablets 1mg [ORGANON] drug res72: Hormone replacement therapy
8770 CPRD_product_code FEMOSTON tablets 2mg + 20mg [ABBOTT] drug res72: Hormone replacement therapy
8837 CPRD_product_code estradiol implant 25mg drug res72: Hormone replacement therapy
9047 CPRD_product_code FEMATRIX 80 patch 80mcg/24 hours (2.5mg/unit) [ABBOTT] drug res72: Hormone replacement therapy
9234 CPRD_product_code EVOREL SEQUI patch 50mcg/24 hours (3.2mg/unit) [JANSSEN] drug res72: Hormone replacement therapy
9268 CPRD_product_code estradiol twice weekly patch 50micrograms/24 hours (4mg/unit) drug res72: Hormone replacement therapy
9413 CPRD_product_code estradiol valerate and (estradiol valerate with norethisterone) tablets 1mg + (1mg + 1mg) drug res72: Hormone replacement therapy
9649 CPRD_product_code ELLESTE-SOLO MX 80 patch 80mcg/24 hours (2.5mg/unit) [MEDA] drug res72: Hormone replacement therapy
986 CPRD_product_code ESTRADERM TTS patch 50micrograms/24 hours (4mg/unit) [NOV/CIBA] drug res72: Hormone replacement therapy
988 CPRD_product_code ESTRADERM TTS patch 25micrograms/24 hours (2mg/unit) [NOV/CIBA] drug res72: Hormone replacement therapy
9901 CPRD_product_code PROGYNOVA TS 100 patch 100mcg/24 hour (7.6mg/unit) [BAYER] drug res72: Hormone replacement therapy
9976 CPRD_product_code estradiol with (estradiol + norethisterone acetate) twice weekly patch 50mcg/24 hr + (50mcg+250mcg/2 drug res72: Hormone replacement therapy

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