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Research article:

Cardiovascular Risk and Risk Factor Management in Type 2 Diabetes: A Population-Based Cohort Study Assessing Sex Disparities

Reference:

Alison K. Wright, Evangelos Kontopantelis, Richard Emsley, Iain Edward Buchan, Mamas A. Mamas, Naveed Sattar, Darren M. Ashcroft, and Martin K. Rutter(2019) Cardiovascular Risk and Risk Factor Management in Type 2 Diabetes: A Population-Based Cohort Study Assessing Sex Disparities. Circulation, doi: 10.1161/CIRCULATIONAHA.118.039100

Link to article
Abstract
Background: With recent changes in UK clinical practice for diabetes care, contemporary estimates of sex disparities in cardiovascular risk and risk factor management are needed. Methods: In this retrospective cohort study, using the Clinical Practice Research Datalink linked to hospital and death records for people in England, we identified 79,985 patients with incident T2DM between 2006-2013 matched to 386,547 patients without diabetes. Sex-stratified Cox models were used to assess cardiovascular risk. Results: Compared to women without T2DM, women with T2DM had a higher cardiovascular event risk (adjusted HR 1.20 [95% CI 1.12-1.28]) with similar corresponding data in men (HR 1.12 [1.06-1.19]) leading to a non-significant higher relative risk in women (risk ratio 1.07 [0.98-1.17]). However, some important sex differences in the management of risk factors were observed. Compared to men with T2DM, women with T2DM were more likely to be obese, hypertensive and have hypercholesterolaemia but were less likely to be prescribed lipid-lowering medication and ACE inhibitors, especially if they had CVD. Conclusions: Compared to men developing T2DM, women with T2DM do not have a significantly higher relative increase in cardiovascular risk, but ongoing sex disparities in prescribing should prompt heightened efforts to improve the standard and equity of diabetes care in women and men.
Author for correspondence
Alison Wright
Email for correspondence
alison.wright@manchester.ac.uk

Code list: res72: Smoking

62 codes in list

Code Coding system Description Entity type List name smoking_status
137..00 Read Tobacco consumption diagnostic res72: Smoking current smoker
1371 Read Never smoked tobacco diagnostic res72: Smoking never smoker
137..11 Read Smoker - amount smoked diagnostic res72: Smoking current smoker
1371.11 Read Non-smoker diagnostic res72: Smoking never smoker
1372 Read Trivial smoker - < 1 cig/day diagnostic res72: Smoking current smoker
1372.11 Read Occasional smoker diagnostic res72: Smoking current smoker
1373 Read Light smoker - 1-9 cigs/day diagnostic res72: Smoking current smoker
1374 Read Moderate smoker - 10-19 cigs/d diagnostic res72: Smoking current smoker
1375 Read Heavy smoker - 20-39 cigs/day diagnostic res72: Smoking current smoker
1376 Read Very heavy smoker - 40+cigs/d diagnostic res72: Smoking current smoker
1377 Read Ex-trivial smoker (<1/day) diagnostic res72: Smoking ex smoker
1378 Read Ex-light smoker (1-9/day) diagnostic res72: Smoking ex smoker
1379 Read Ex-moderate smoker (10-19/day) diagnostic res72: Smoking ex smoker
137a.00 Read Pipe tobacco consumption diagnostic res72: Smoking current smoker
137A.00 Read Ex-heavy smoker (20-39/day) diagnostic res72: Smoking ex smoker
137b.00 Read Ready to stop smoking diagnostic res72: Smoking current smoker
137B.00 Read Ex-very heavy smoker (40+/day) diagnostic res72: Smoking ex smoker
137c.00 Read Thinking about stopping smoking diagnostic res72: Smoking current smoker
137C.00 Read Keeps trying to stop smoking diagnostic res72: Smoking current smoker
137d.00 Read Not interested in stopping smoking diagnostic res72: Smoking current smoker
137D.00 Read Admitted tobacco cons untrue ? diagnostic res72: Smoking current smoker
137e.00 Read Smoking restarted diagnostic res72: Smoking current smoker
137E.00 Read Tobacco consumption unknown diagnostic res72: Smoking current smoker
137F.00 Read Ex-smoker - amount unknown diagnostic res72: Smoking ex smoker
137G.00 Read Trying to give up smoking diagnostic res72: Smoking current smoker
137H.00 Read Pipe smoker diagnostic res72: Smoking current smoker
137I.00 Read Passive smoker diagnostic res72: Smoking never smoker
137j.00 Read Ex-cigarette smoker diagnostic res72: Smoking ex smoker
137J.00 Read Cigar smoker diagnostic res72: Smoking current smoker
137K.00 Read Stopped smoking diagnostic res72: Smoking ex smoker
137K000 Read Recently stopped smoking diagnostic res72: Smoking ex smoker
137l.00 Read Ex roll-up cigarette smoker diagnostic res72: Smoking ex smoker
137L.00 Read Current non-smoker diagnostic res72: Smoking never smoker
137m.00 Read Failed attempt to stop smoking diagnostic res72: Smoking current smoker
137M.00 Read Rolls own cigarettes diagnostic res72: Smoking current smoker
137N.00 Read Ex pipe smoker diagnostic res72: Smoking ex smoker
137O.00 Read Ex cigar smoker diagnostic res72: Smoking ex smoker
137P.00 Read Cigarette smoker diagnostic res72: Smoking current smoker
137P.11 Read Smoker diagnostic res72: Smoking current smoker
137Q.00 Read Smoking started diagnostic res72: Smoking current smoker
137Q.11 Read Smoking restarted diagnostic res72: Smoking current smoker
137R.00 Read Current smoker diagnostic res72: Smoking current smoker
137S.00 Read Ex smoker diagnostic res72: Smoking ex smoker
137T.00 Read Date ceased smoking diagnostic res72: Smoking ex smoker
137U.00 Read Not a passive smoker diagnostic res72: Smoking never smoker
137V.00 Read Smoking reduced diagnostic res72: Smoking current smoker
137W.00 Read Chews tobacco diagnostic res72: Smoking current smoker
137X.00 Read Cigarette consumption diagnostic res72: Smoking current smoker
137Y.00 Read Cigar consumption diagnostic res72: Smoking current smoker
137Z.00 Read Tobacco consumption NOS diagnostic res72: Smoking current smoker
8CAL.00 Read Smoking cessation advice diagnostic res72: Smoking current smoker
8H7i.00 Read Referral to smoking cessation advisor diagnostic res72: Smoking current smoker
8HkQ.00 Read Referral to NHS stop smoking service diagnostic res72: Smoking current smoker
8HTK.00 Read Referral to stop-smoking clinic diagnostic res72: Smoking current smoker
8IAj.00 Read Smoking cessation advice declined diagnostic res72: Smoking current smoker
9km..00 Read Ex-smoker annual review - enhanced services administration diagnostic res72: Smoking ex smoker
9km..11 Read Ex-smoker annual review diagnostic res72: Smoking ex smoker
9kn..00 Read Non-smoker annual review - enhanced services administration diagnostic res72: Smoking never smoker
9kn..11 Read Non-smoker annual review diagnostic res72: Smoking never smoker
9ko..00 Read Current smoker annual review - enhanced services admin diagnostic res72: Smoking current smoker
9ko..11 Read Current smoker annual review diagnostic res72: Smoking current smoker
9NS0200 Read Referral for smoking cessation service offered diagnostic res72: Smoking current smoker

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