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Research article:
Glucose, blood pressure and cholesterol levels and their relationships to clinical outcomes in type 2 diabetes: a retrospective cohort study
Reference:
Evangelos Kontopantelis, David A Springate, David Reeves, Darren M Ashcroft, Martin Rutter, Iain Buchan, Tim Doran(2015) Glucose, blood pressure and cholesterol levels and their relationships to clinical outcomes in type 2 diabetes: a retrospective cohort study. Diabetologia, doi: 10.1007/s00125-014-3473-8
- Link to fulltext article
- Abstract
- Background: Observational data have been used to inform target levels for modifiable risk factors in type 2 diabetes but these data are limited by confounding. We aimed to describe the shape of observed relationships between risk factor levels and clinically important outcomes in type 2 diabetes after adjusting for multiple confounders. Methods: We used retrospective longitudinal data on 246,544 adults with type 2 diabetes from 600 practices contributing to the Clinical Practice Research Datalink between 2006 and 2012. Proportional hazards regression models quantified the risks of mortality, microvascular or macrovascular events associated with four modifiable risk factors: glycated haemoglobin (HbA1c), systolic and diastolic blood pressure and total cholesterol, while controlling for numerous patient and practice covariates. Findings: U-shaped relationships were observed between all-cause mortality and levels of the four risk factors. The lowest risks were associated with HbA1c 7.25-7.75%; total cholesterol 3.5-4.5 mmol/L; systolic blood pressure 135-145 mmHg; and diastolic blood pressure 82.5-87.5 mmHg. coronary and stroke mortality related to the four risk factors in a positive, curvilinear way, with the exception of blood pressure which related to coronary deaths in a U-shape. Macrovascular events showed a positive and curvilinear relationship with HbA1c but U-shaped for total cholesterol and systolic blood pressure. Microvascular related to the four risk factors in a curvilinear way: positive for HbA1c and systolic blood pressure but negative for cholesterol and diastolic blood pressure. Interpretation: We identified several relationships which, when considered in the light of relevant trial data, support a call for major changes to clinical practice. Most importantly, our results support trial data indicating that normalisation of glucose and blood pressure can lead to poorer outcomes, which makes a strong case for target ranges for these risk factors rather than target levels.
- Author for correspondence
- Evangelos Kontopantelis
- Email for correspondence
- E.Kontopantelis@manchester.ac.uk
Code list: res9: diuretics_thiazide
282 codes in list
| Code | Coding system | Description | Entity type | List name | multilexcode | bnfcode | bnfchapter |
|---|---|---|---|---|---|---|---|
| 1021 | CPRD_product_code | INNOZIDE tablets [M S D] | drug | res9: diuretics_thiazide | 727001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 10316 | CPRD_product_code | COAPROVEL tablets 150mg + 12.5mg [SANOFI BMS] | drug | res9: diuretics_thiazide | 10707001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 10323 | CPRD_product_code | losartan with hydrochlorothiazide tablets 100mg + 25mg | drug | res9: diuretics_thiazide | 13477001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 10627 | CPRD_product_code | CO-BETALOC tablets 100mg + 12.5mg [PHARMACIA] | drug | res9: diuretics_thiazide | 180001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 10902 | CPRD_product_code | captopril with hydrochlorothiazide tablets 50mg + 25mg | drug | res9: diuretics_thiazide | 5130001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 11133 | CPRD_product_code | hydrochlorothiazide with captopril tablets 25mg + 50mg | drug | res9: diuretics_thiazide | 5446001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 1124 | CPRD_product_code | TENORETIC tablets 100mg + 25mg [ASTRAZENEC] | drug | res9: diuretics_thiazide | 1698001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 1125 | CPRD_product_code | NAVIDREX -K tablets [NOV/CIBA] | drug | res9: diuretics_thiazide | 627001 | 2020100 | Thiazides and related diuretics |
| 11338 | CPRD_product_code | bendroflumethiazide with nadolol tablets 5mg + 40mg | drug | res9: diuretics_thiazide | 4987001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 11351 | CPRD_product_code | co-zidocapt (hydrochlorothiazide and captopril) tablets 25mg + 50mg | drug | res9: diuretics_thiazide | 10938001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 11384 | CPRD_product_code | co-flumactone (hydroflumethiazide and spironolactone) tablets 50mg+50mg | drug | res9: diuretics_thiazide | 6788002 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 11448 | CPRD_product_code | irbesartan with hydrochlorothiazide tablets 150mg + 12.5mg | drug | res9: diuretics_thiazide | 8910001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 11469 | CPRD_product_code | irbesartan with hydrochlorothiazide tablets 300mg + 12.5mg | drug | res9: diuretics_thiazide | 8910002 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 11526 | CPRD_product_code | COAPROVEL tablets 300mg + 12.5mg [SANOFI BMS] | drug | res9: diuretics_thiazide | 10707002 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 11561 | CPRD_product_code | co-zidocapt (hydrochlorothiazide and captopril) tablets 12.5mg + 25mg | drug | res9: diuretics_thiazide | 10938002 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 11641 | CPRD_product_code | captopril with hydrochlorothiazide tablets 25mg + 12.5mg | drug | res9: diuretics_thiazide | 5130002 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 1170 | CPRD_product_code | cyclopenthiazide tablets 0.5mg | drug | res9: diuretics_thiazide | 3412001 | 2020100 | Thiazides and related diuretics |
| 11864 | CPRD_product_code | valsartan with hydrochlorothiazide tablets 160mg + 12.5mg | drug | res9: diuretics_thiazide | 12571001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 12054 | CPRD_product_code | propranolol with bendroflumethiazide capsules 80mg + 2.5mg | drug | res9: diuretics_thiazide | 5577001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 1209 | CPRD_product_code | NEO-NACLEX tablets 5mg [GOLDSHIELD] | drug | res9: diuretics_thiazide | 631001 | 2020100 | Thiazides and related diuretics |
| 1211 | CPRD_product_code | bendroflumethiazide with potassium modified release tablet 2.5mg + 8.4mmol | drug | res9: diuretics_thiazide | 4905001 | 2020800 | Diuretic/potassium supplement combinations |
| 12110 | CPRD_product_code | hydroflumethiazide tablets 50mg | drug | res9: diuretics_thiazide | 3796001 | 2020100 | Thiazides and related diuretics |
| 1213 | CPRD_product_code | NEO-NACLEX -K tablets [MERCURY] | drug | res9: diuretics_thiazide | 632001 | 2020800 | Diuretic/potassium supplement combinations |
| 12360 | CPRD_product_code | NEPHRIL tablets 1mg [PFIZER] | drug | res9: diuretics_thiazide | 633001 | 2020100 | Thiazides and related diuretics |
| 12440 | CPRD_product_code | HYDROSALURIC tablets 25mg [M S D] | drug | res9: diuretics_thiazide | 3790001 | 2020100 | Thiazides and related diuretics |
| 1251 | CPRD_product_code | MODURET 25 tablets [M S D] | drug | res9: diuretics_thiazide | 2513001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 12517 | CPRD_product_code | timolol maleate with bendroflumethiazide tablets 20mg + 5mg | drug | res9: diuretics_thiazide | 4838002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 12546 | CPRD_product_code | KALSPARE tablets [DOMINION] | drug | res9: diuretics_thiazide | 1268001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 12547 | CPRD_product_code | triamterene with chlortalidone tablets 50mg + 50mg | drug | res9: diuretics_thiazide | 4876001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 12651 | CPRD_product_code | timolol maleate with bendroflumethiazide tablets 10mg + 2.5mg | drug | res9: diuretics_thiazide | 4838001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 1288 | CPRD_product_code | TENORET tablets 50mg + 12.5mg [ASTRAZENEC] | drug | res9: diuretics_thiazide | 931001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 12926 | CPRD_product_code | polythiazide tablets 1mg | drug | res9: diuretics_thiazide | 4530001 | 2020100 | Thiazides and related diuretics |
| 1297 | CPRD_product_code | ALDACTIDE film coated tablets 50mg + 50mg [PHARMACIA] | drug | res9: diuretics_thiazide | 2363002 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 13246 | CPRD_product_code | chlorothiazide oral suspension 150mg/5ml | drug | res9: diuretics_thiazide | 13958001 | 2020100 | Thiazides and related diuretics |
| 13363 | CPRD_product_code | ESIDREX tablets 50mg [NOV/CIBA] | drug | res9: diuretics_thiazide | 322002 | 2020100 | Thiazides and related diuretics |
| 13525 | CPRD_product_code | HYDRENOX tablets 50mg [KNOLL] | drug | res9: diuretics_thiazide | 2574001 | 2020100 | Thiazides and related diuretics |
| 13526 | CPRD_product_code | ATENIXCO tablets 100mg + 25mg [ASHBOURNE] | drug | res9: diuretics_thiazide | 3929002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 13871 | CPRD_product_code | co-prenozide (oxprenolol and cyclopenthiazide) modified release tablet 160mg + 0.25mg | drug | res9: diuretics_thiazide | 6790001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 14126 | CPRD_product_code | acebutolol hydrochloride and hydrochlorothiazide tablets 200mg + 12.5mg | drug | res9: diuretics_thiazide | 3009001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 14228 | CPRD_product_code | COVERSYL PLUS tablets [SERVIER] | drug | res9: diuretics_thiazide | 11044001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 14283 | CPRD_product_code | valsartan with hydrochlorothiazide tablets 160mg + 25mg | drug | res9: diuretics_thiazide | 12575001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 14438 | CPRD_product_code | CORGARETIC 80 tablets [SANOFI S] | drug | res9: diuretics_thiazide | 1632001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 14738 | CPRD_product_code | hydrochlorothiazide with losartan tablets 12.5mg + 50mg | drug | res9: diuretics_thiazide | 8422001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 14870 | CPRD_product_code | telmisartan with hydrochlorothiazide tablets 40mg + 12.5mg | drug | res9: diuretics_thiazide | 9452001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 15031 | CPRD_product_code | ACCURETIC tablets 10mg + 12.5mg [PFIZER] | drug | res9: diuretics_thiazide | 6897001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 15108 | CPRD_product_code | quinapril and hydrochlorothiazide tablets 10mg + 12.5mg | drug | res9: diuretics_thiazide | 6898001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 15127 | CPRD_product_code | hydrochlorothiazide with triamterene tablets 25mg+50mg | drug | res9: diuretics_thiazide | 3789001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 15135 | CPRD_product_code | hydrochlorothiazide with captopril tablets 12.5mg + 25mg | drug | res9: diuretics_thiazide | 5446002 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 1520 | CPRD_product_code | CAPOZIDE tablets [SQUIBB] | drug | res9: diuretics_thiazide | 5131001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 15457 | CPRD_product_code | BAYCARON tablets 25mg [BAYER] | drug | res9: diuretics_thiazide | 83001 | 2020100 | Thiazides and related diuretics |
| 15488 | CPRD_product_code | metoprolol tartrate with chlortalidone tablets | drug | res9: diuretics_thiazide | 5364001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 15811 | CPRD_product_code | co-flumactone (hydroflumethiazide and spironolactone) tablets 25mg+25mg | drug | res9: diuretics_thiazide | 6788001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 16060 | CPRD_product_code | valsartan with hydrochlorothiazide tablets 80mg + 12.5mg | drug | res9: diuretics_thiazide | 12785001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 16161 | CPRD_product_code | telmisartan with hydrochlorothiazide tablets 80mg + 12.5mg | drug | res9: diuretics_thiazide | 2748001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 16498 | CPRD_product_code | KALSPARE tablets [DHP] | drug | res9: diuretics_thiazide | 5382001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 16632 | CPRD_product_code | HYDROSALURIC tablets 50mg [M S D] | drug | res9: diuretics_thiazide | 3790002 | 2020100 | Thiazides and related diuretics |
| 16786 | CPRD_product_code | chlortalidone with atenolol tablets 25mg+100mg | drug | res9: diuretics_thiazide | 3316002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 17143 | CPRD_product_code | mefruside tablets 25mg | drug | res9: diuretics_thiazide | 4091001 | 2020100 | Thiazides and related diuretics |
| 1721 | CPRD_product_code | DYAZIDE tablets [MERCURY] | drug | res9: diuretics_thiazide | 290001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 17252 | CPRD_product_code | ESIDREX tablets 25mg [NOV/CIBA] | drug | res9: diuretics_thiazide | 322001 | 2020100 | Thiazides and related diuretics |
| 17561 | CPRD_product_code | bendroflumethiazide with potassium modified release tablet 2.5mg + 7.7mmol | drug | res9: diuretics_thiazide | 4905002 | 2020800 | Diuretic/potassium supplement combinations |
| 17655 | CPRD_product_code | CARACE 10 plus tablets [BMS] | drug | res9: diuretics_thiazide | 6251002 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 17689 | CPRD_product_code | MICARDIS PLUS tablets 80mg + 12.5mg [BOEH INGL] | drug | res9: diuretics_thiazide | 313001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 17720 | CPRD_product_code | SALURIC tablets 500mg [M S D] | drug | res9: diuretics_thiazide | 838001 | 2020100 | Thiazides and related diuretics |
| 1788 | CPRD_product_code | atenolol with chlortalidone tablets 100mg+25mg | drug | res9: diuretics_thiazide | 4978002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 18200 | CPRD_product_code | olmesartan medoxomil with hydrochlorothiazide tablets 20mg + 12.5mg | drug | res9: diuretics_thiazide | 13906001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 18202 | CPRD_product_code | MICARDIS PLUS tablets 40mg + 12.5mg [BOEH INGL] | drug | res9: diuretics_thiazide | 9450001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 18263 | CPRD_product_code | ACEZIDE tablets [SQUIBB] | drug | res9: diuretics_thiazide | 2939001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 18267 | CPRD_product_code | ENDURON tablets 5mg [ABBOTT] | drug | res9: diuretics_thiazide | 4138001 | 2020100 | Thiazides and related diuretics |
| 18287 | CPRD_product_code | CO-BETALOC SA tablets 200mg + 25mg [PHARMACIA] | drug | res9: diuretics_thiazide | 1399001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 18361 | CPRD_product_code | AMILMAXCO tablets [ASHBOURNE] | drug | res9: diuretics_thiazide | 6366001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 18606 | CPRD_product_code | diltiazem and hydrochlorothiazide modified release capsules 150mg + 12.5mg | drug | res9: diuretics_thiazide | 9566001 | 02020100/02060200 | Thiazides and related diuretics/Calcium channel blockers |
| 18726 | CPRD_product_code | TRIAMAXCO tablets [ASHBOURNE] | drug | res9: diuretics_thiazide | 3930001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 18733 | CPRD_product_code | co-amilozide (amiloride and hydrochlorothiazide) oral solution 5mg + 50mg/5ml | drug | res9: diuretics_thiazide | 5853003 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 18743 | CPRD_product_code | TENBEN capsules 25mg + 1.25mg [GALEN] | drug | res9: diuretics_thiazide | 10711001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 18903 | CPRD_product_code | olmesartan medoxomil with hydrochlorothiazide tablets 20mg + 25mg | drug | res9: diuretics_thiazide | 13907001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 18973 | CPRD_product_code | CENTYL tablets 2.5mg [BURGESS] | drug | res9: diuretics_thiazide | 1056001 | 2020100 | Thiazides and related diuretics |
| 19055 | CPRD_product_code | chlortalidone with atenolol tablets 12.5mg+50mg | drug | res9: diuretics_thiazide | 3316001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 19142 | CPRD_product_code | bendroflumethiazide with timolol maleate tablets 2.5mg + 10mg | drug | res9: diuretics_thiazide | 4988001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 19890 | CPRD_product_code | hydrochlorothiazide with amiloride tablets 25mg+2.5mg | drug | res9: diuretics_thiazide | 3788001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 2 | CPRD_product_code | bendroflumethiazide tablets 2.5mg | drug | res9: diuretics_thiazide | 2782001 | 2020100 | Thiazides and related diuretics |
| 2001 | CPRD_product_code | ALDACTIDE film coated tablets 25mg + 25mg [PHARMACIA] | drug | res9: diuretics_thiazide | 2363001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 2002 | CPRD_product_code | amiloride hydrochloride with hydrochlorothiazide tablets 5mg + 50mg | drug | res9: diuretics_thiazide | 5453001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 20057 | CPRD_product_code | methyclothiazide tablets 5mg | drug | res9: diuretics_thiazide | 4137001 | 2020100 | Thiazides and related diuretics |
| 20066 | CPRD_product_code | AMIL-CO tablets 5mg + 50mg [IVAX] | drug | res9: diuretics_thiazide | 3791001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 20093 | CPRD_product_code | metoprolol tartrate with hydrochlorothiazide modified release tablet 200mg + 25mg | drug | res9: diuretics_thiazide | 5365001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 20426 | CPRD_product_code | CENTYL K tablets 2.5mg + 7.7mmol [BURGESS] | drug | res9: diuretics_thiazide | 158002 | 2020800 | Diuretic/potassium supplement combinations |
| 20431 | CPRD_product_code | CENTYL K tablets 2.5mg + 7.7mmol [LEO] | drug | res9: diuretics_thiazide | 8187001 | 2020800 | Diuretic/potassium supplement combinations |
| 2046 | CPRD_product_code | NAVIDREX tablets 0.5mg [MERCURY] | drug | res9: diuretics_thiazide | 626001 | 2020100 | Thiazides and related diuretics |
| 21025 | CPRD_product_code | PRESTIM FORTE tablets [LEO] | drug | res9: diuretics_thiazide | 4840001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 21182 | CPRD_product_code | hydrochlorothiazide with timolol and amiloride tablets 25mg + 10mg + 2.5mg | drug | res9: diuretics_thiazide | 5450001 | 02020100/02020300/02040000 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Beta-blocker |
| 21231 | CPRD_product_code | CARALPHA tablets 20mg + 12.5mg [ACTAVIS] | drug | res9: diuretics_thiazide | 12484001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 21423 | CPRD_product_code | COZAAR-COMP tablets 100mg + 25mg [M S D] | drug | res9: diuretics_thiazide | 13479001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 21803 | CPRD_product_code | BERKOZIDE tablets 2.5mg [BERK] | drug | res9: diuretics_thiazide | 105001 | 2020100 | Thiazides and related diuretics |
| 21867 | CPRD_product_code | BERKOZIDE tablets 5mg [BERK] | drug | res9: diuretics_thiazide | 105002 | 2020100 | Thiazides and related diuretics |
| 21873 | CPRD_product_code | ATENIXCO tablets 50mg+12.5mg [ASHBOURNE] | drug | res9: diuretics_thiazide | 3929001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 2255 | CPRD_product_code | NAVISPARE tablets [MERCURY] | drug | res9: diuretics_thiazide | 6598001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 22912 | CPRD_product_code | bendroflumethiazide with propranolol capsules 2.5mg + 80mg | drug | res9: diuretics_thiazide | 4985001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 22923 | CPRD_product_code | hydrochlorothiazide with amiloride tablets 50mg + 5mg | drug | res9: diuretics_thiazide | 3788003 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 23131 | CPRD_product_code | bendroflumethiazide with propranolol modified release capsules 5mg + 160mg | drug | res9: diuretics_thiazide | 4985002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 23134 | CPRD_product_code | nadolol with bendroflumethiazide tablets 40mg + 5mg | drug | res9: diuretics_thiazide | 4234001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 23427 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 5mg [HILLCROSS] | drug | res9: diuretics_thiazide | 209010 | 2020100 | Thiazides and related diuretics |
| 23456 | CPRD_product_code | hydrochlorothiazide with valsartan tablets 25mg + 160mg | drug | res9: diuretics_thiazide | 12577001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 23505 | CPRD_product_code | ADIZEM XL PLUS controlled release capsules 150mg + 12.5mg [NAPP] | drug | res9: diuretics_thiazide | 9565001 | 02020100/02060200 | Thiazides and related diuretics/Calcium channel blockers |
| 24008 | CPRD_product_code | VASETIC tablets [SHIRE] | drug | res9: diuretics_thiazide | 6394001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 24189 | CPRD_product_code | NEO-BENDROMAX tablets 2.5mg [ASHBOURNE] | drug | res9: diuretics_thiazide | 7263001 | 2020100 | Thiazides and related diuretics |
| 24190 | CPRD_product_code | NEO-BENDROMAX tablets 5mg [ASHBOURNE] | drug | res9: diuretics_thiazide | 7263002 | 2020100 | Thiazides and related diuretics |
| 24268 | CPRD_product_code | hydrochlorothiazide with valsartan tablets 12.5mg + 80mg | drug | res9: diuretics_thiazide | 12786001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 24280 | CPRD_product_code | TOTARETIC tablets 100mg+25mg [CP PHARM] | drug | res9: diuretics_thiazide | 8920002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 24484 | CPRD_product_code | hydrochlorothiazide with valsartan tablets 12.5mg + 160mg | drug | res9: diuretics_thiazide | 12572001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 24632 | CPRD_product_code | hydrochlorothiazide with losartan tablets 25mg + 100mg | drug | res9: diuretics_thiazide | 13478001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 25363 | CPRD_product_code | PRESTIM tablets [MEDA] | drug | res9: diuretics_thiazide | 12711001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 25382 | CPRD_product_code | CO-DIOVAN tablets 160mg + 25mg [NOVARTIS] | drug | res9: diuretics_thiazide | 12578001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 25500 | CPRD_product_code | HYPERTANE 50 tablets [SCHWARZ] | drug | res9: diuretics_thiazide | 5134001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 25505 | CPRD_product_code | SPIRO-CO tablets 50mg+50mg [IVAX] | drug | res9: diuretics_thiazide | 7196002 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 25730 | CPRD_product_code | timolol maleate with amiloride and hydrochlorothiazide tablets | drug | res9: diuretics_thiazide | 5448001 | 02020100/02020300/02040000 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Beta-blocker |
| 2612 | CPRD_product_code | indapamide tablets 2.5mg | drug | res9: diuretics_thiazide | 3870001 | 2020100 | Thiazides and related diuretics |
| 26219 | CPRD_product_code | ZIDA-CO tablets 5mg + 50mg [OPUS] | drug | res9: diuretics_thiazide | 8788001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 26220 | CPRD_product_code | DELVAS tablets [BERK] | drug | res9: diuretics_thiazide | 5096001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 26248 | CPRD_product_code | TENCHLOR tablets 100mg + 25mg [BERK] | drug | res9: diuretics_thiazide | 2289002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 26256 | CPRD_product_code | OPUMIDE tablets 2.5mg [OPUS] | drug | res9: diuretics_thiazide | 8392001 | 2020100 | Thiazides and related diuretics |
| 26275 | CPRD_product_code | NINDAXA tablets 2.5mg [ASHBOURNE] | drug | res9: diuretics_thiazide | 7329001 | 2020100 | Thiazides and related diuretics |
| 26741 | CPRD_product_code | TOTARETIC tablets 50mg+12.5mg [CP PHARM] | drug | res9: diuretics_thiazide | 8920001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 27256 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 2.5mg [WOCKHARDT] | drug | res9: diuretics_thiazide | 207009 | 2020100 | Thiazides and related diuretics |
| 27520 | CPRD_product_code | OLMETEC PLUS tablets 20mg + 25mg [DAIIC-SANK] | drug | res9: diuretics_thiazide | 13910001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 27689 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 2.5mg [IVAX] | drug | res9: diuretics_thiazide | 2442009 | 2020100 | Thiazides and related diuretics |
| 27946 | CPRD_product_code | nadolol with bendroflumethiazide tablets 80mg + 5mg | drug | res9: diuretics_thiazide | 4234002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 27957 | CPRD_product_code | NATRAMID tablets 2.5mg [TRINITY] | drug | res9: diuretics_thiazide | 8181001 | 2020100 | Thiazides and related diuretics |
| 28157 | CPRD_product_code | KALSPARE LS tablets [DOMINION] | drug | res9: diuretics_thiazide | 1268002 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 28177 | CPRD_product_code | hydrochlorothiazide with atenolol and amiloride capsules | drug | res9: diuretics_thiazide | 5328001 | 02020100/02020300/02040000 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Beta-blocker |
| 2833 | CPRD_product_code | cyclopenthiazide -k tablets | drug | res9: diuretics_thiazide | 3413001 | 2020100 | Thiazides and related diuretics |
| 29427 | CPRD_product_code | hydrochlorothiazide with metoprolol tartrate tablets 12.5mg + 100mg | drug | res9: diuretics_thiazide | 5366002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 29529 | CPRD_product_code | hydroflumethiazide with spironolactone tablets 25mg+25mg | drug | res9: diuretics_thiazide | 3797001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 29634 | CPRD_product_code | OLMETEC PLUS tablets 20mg + 12.5mg [DAIIC-SANK] | drug | res9: diuretics_thiazide | 13909001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 2979 | CPRD_product_code | CENTYL K tablets [BURGESS] | drug | res9: diuretics_thiazide | 158001 | 2020800 | Diuretic/potassium supplement combinations |
| 2982 | CPRD_product_code | ZESTORETIC 20-tablets 20mg + 12.5mg [ASTRAZENEC] | drug | res9: diuretics_thiazide | 837001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 29991 | CPRD_product_code | CENTYL tablets 5mg [BURGESS] | drug | res9: diuretics_thiazide | 1056002 | 2020100 | Thiazides and related diuretics |
| 30272 | CPRD_product_code | benzthiazide with triamterene capsules | drug | res9: diuretics_thiazide | 4025001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 30519 | CPRD_product_code | amiloride hydrochloride with timolol and hydrochlorothiazide tablets | drug | res9: diuretics_thiazide | 5449001 | 02020100/02020300/02040000 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Beta-blocker |
| 3056 | CPRD_product_code | NATRILIX SR sustained release tablets 1.5mg [SERVIER] | drug | res9: diuretics_thiazide | 10762001 | 2020100 | Thiazides and related diuretics |
| 31131 | CPRD_product_code | SPIRO-CO tablets 25mg+25mg [IVAX] | drug | res9: diuretics_thiazide | 7196001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 31150 | CPRD_product_code | CO-AMILOZIDE tablets 5mg+50mg [IVAX] | drug | res9: diuretics_thiazide | 319009 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 31470 | CPRD_product_code | TENCHLOR tablets 50mg+12.5mg [BERK] | drug | res9: diuretics_thiazide | 2289001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 31670 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 2.5mg [TEVA] | drug | res9: diuretics_thiazide | 1663010 | 2020100 | Thiazides and related diuretics |
| 31708 | CPRD_product_code | CO-TENIDONE tablets 50mg+12.5mg [ACTAVIS] | drug | res9: diuretics_thiazide | 2230009 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 31820 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 5mg [WOCKHARDT] | drug | res9: diuretics_thiazide | 207010 | 2020100 | Thiazides and related diuretics |
| 3203 | CPRD_product_code | CAPOZIDE LS tablets [SQUIBB] | drug | res9: diuretics_thiazide | 5131002 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 32094 | CPRD_product_code | CO-TENIDONE tablets 50mg+12.5mg [HILLCROSS] | drug | res9: diuretics_thiazide | 1363009 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 32166 | CPRD_product_code | CAPTO-CO tablets 25mg+50mg [IVAX] | drug | res9: diuretics_thiazide | 9259002 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 3293 | CPRD_product_code | MODURETIC solution [BMS] | drug | res9: diuretics_thiazide | 594002 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 33083 | CPRD_product_code | INDAPAMIDE tablets 2.5mg [TEVA] | drug | res9: diuretics_thiazide | 2195009 | 2020100 | Thiazides and related diuretics |
| 33353 | CPRD_product_code | LISINOPRIL AND HYDROCHLOROTHIAZIDE tablets 20mg + 12.5mg [TEVA] | drug | res9: diuretics_thiazide | 5007009 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 33415 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 2.5mg [GEN (UK)] | drug | res9: diuretics_thiazide | 3780009 | 2020100 | Thiazides and related diuretics |
| 33651 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 2.5mg [HILLCROSS] | drug | res9: diuretics_thiazide | 209009 | 2020100 | Thiazides and related diuretics |
| 33659 | CPRD_product_code | hydrochlorothiazide with metoprolol tartrate modified release tablet 25mg + 200mg | drug | res9: diuretics_thiazide | 5366001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 33724 | CPRD_product_code | DIURIL oral suspension 250mg/5ml [M S D] | drug | res9: diuretics_thiazide | 12044001 | 2020100 | Thiazides and related diuretics |
| 34012 | CPRD_product_code | CO-TENIDONE tablets 100mg+25mg [IVAX] | drug | res9: diuretics_thiazide | 1818009 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 34034 | CPRD_product_code | CO-TENIDONE tablets 50mg+12.5mg [IVAX] | drug | res9: diuretics_thiazide | 1818010 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 34059 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 2.5mg [ACTAVIS] | drug | res9: diuretics_thiazide | 1855010 | 2020100 | Thiazides and related diuretics |
| 34124 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 5mg [ACTAVIS] | drug | res9: diuretics_thiazide | 1855009 | 2020100 | Thiazides and related diuretics |
| 34367 | CPRD_product_code | CO-AMILOZIDE tablets 2.5mg+25mg [WOCKHARDT] | drug | res9: diuretics_thiazide | 1752010 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 34449 | CPRD_product_code | CO-TENIDONE tablets 50mg+12.5mg [GEN (UK)] | drug | res9: diuretics_thiazide | 3104009 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 34551 | CPRD_product_code | INDAPAMIDE tablets 2.5mg [GEN (UK)] | drug | res9: diuretics_thiazide | 3137009 | 2020100 | Thiazides and related diuretics |
| 34602 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 2.5mg [SOVEREIGN] | drug | res9: diuretics_thiazide | 4678009 | 2020100 | Thiazides and related diuretics |
| 348 | CPRD_product_code | MODURETIC tablets [BMS] | drug | res9: diuretics_thiazide | 594001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 34803 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 2.5mg [REGENT] | drug | res9: diuretics_thiazide | 3686009 | 2020100 | Thiazides and related diuretics |
| 34825 | CPRD_product_code | CO-TENIDONE tablets 50mg+12.5mg [TEVA] | drug | res9: diuretics_thiazide | 1655009 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 34899 | CPRD_product_code | CO-TENIDONE tablets 100mg+25mg [HILLCROSS] | drug | res9: diuretics_thiazide | 1363010 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 3517 | CPRD_product_code | hydrochlorothiazide tablets 50mg | drug | res9: diuretics_thiazide | 3787002 | 2020100 | Thiazides and related diuretics |
| 35196 | CPRD_product_code | COAPROVEL tablets 300mg + 25mg [SANOFI BMS] | drug | res9: diuretics_thiazide | 14781001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 3526 | CPRD_product_code | amiloride hydrochloride with atenolol and hydrochlorothiazide capsules | drug | res9: diuretics_thiazide | 5454001 | 02020100/02020300/02040000 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Beta-blocker |
| 35380 | CPRD_product_code | hydrochlorothiazide with olmesartan medoxomil tablets 12.5mg + 20mg | drug | res9: diuretics_thiazide | 13960001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 35481 | CPRD_product_code | irbesartan with hydrochlorothiazide tablets 300mg + 25mg | drug | res9: diuretics_thiazide | 14780001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 36519 | CPRD_product_code | ESIDREX -K tablets [NOV/CIBA] | drug | res9: diuretics_thiazide | 323001 | 2020800 | Diuretic/potassium supplement combinations |
| 3701 | CPRD_product_code | amiloride hydrochloride with hydrochlorothiazide tablets 2.5mg+25mg | drug | res9: diuretics_thiazide | 5453002 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 37294 | CPRD_product_code | triamterene with chlortalidone tablets 50mg + 25mg | drug | res9: diuretics_thiazide | 4876002 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 37650 | CPRD_product_code | losartan with hydrochlorothiazide tablets 100mg + 12.5mg | drug | res9: diuretics_thiazide | 15821001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 37710 | CPRD_product_code | LISINOPRIL AND HYDROCHLOROTHIAZIDE tablets 10mg + 12.5mg [TEVA] | drug | res9: diuretics_thiazide | 5006009 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 37725 | CPRD_product_code | CO-TENIDONE tablets 100mg+25mg [GEN (UK)] | drug | res9: diuretics_thiazide | 3104010 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 37747 | CPRD_product_code | COZAAR-COMP tablets 100mg + 12.5mg [M S D] | drug | res9: diuretics_thiazide | 15823001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 37908 | CPRD_product_code | COVERSYL ARGININE PLUS tablets 5mg + 1.25mg [SERVIER] | drug | res9: diuretics_thiazide | 15964001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 37978 | CPRD_product_code | perindopril arginine with indapamide tablets 5mg + 1.25mg | drug | res9: diuretics_thiazide | 15746001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 38367 | CPRD_product_code | hydrochlorothiazide with losartan tablets 12.5mg + 100mg | drug | res9: diuretics_thiazide | 15822001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 38459 | CPRD_product_code | telmisartan with hydrochlorothiazide tablets 80mg + 25mg | drug | res9: diuretics_thiazide | 16278001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 38889 | CPRD_product_code | MICARDIS PLUS tablets 80mg + 25mg [BOEH INGL] | drug | res9: diuretics_thiazide | 16279001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 38995 | CPRD_product_code | ZESTORETIC 20 tablets [ASTRAZENEC] | drug | res9: diuretics_thiazide | 16551001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 39021 | CPRD_product_code | hydrochlorothiazide with olmesartan medoxomil tablets 25mg + 20mg | drug | res9: diuretics_thiazide | 13959001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 39137 | CPRD_product_code | ZESTORETIC 10 tablets [ASTRAZENEC] | drug | res9: diuretics_thiazide | 16550001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 39147 | CPRD_product_code | CARACE 20 PLUS tablets [M S D] | drug | res9: diuretics_thiazide | 16563001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 39227 | CPRD_product_code | CAPOZIDE LS tablets [BMS] | drug | res9: diuretics_thiazide | 16376001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 39242 | CPRD_product_code | CARACE 10 PLUS tablets [M S D] | drug | res9: diuretics_thiazide | 16564001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 39447 | CPRD_product_code | VARBIM XL prolonged release tablet 1.5mg [TEVA] | drug | res9: diuretics_thiazide | 16588001 | 2020100 | Thiazides and related diuretics |
| 40149 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 5mg [IVAX] | drug | res9: diuretics_thiazide | 2443009 | 2020100 | Thiazides and related diuretics |
| 4034 | CPRD_product_code | amiloride hydrochloride with hydrochlorothiazide solution 5mg + 50mg/5ml | drug | res9: diuretics_thiazide | 5453003 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 4044 | CPRD_product_code | DIUREXAN tablets 20mg [MEDA] | drug | res9: diuretics_thiazide | 265001 | 2020100 | Thiazides and related diuretics |
| 40886 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 2.5mg [ALMUS] | drug | res9: diuretics_thiazide | 5110009 | 2020100 | Thiazides and related diuretics |
| 40907 | CPRD_product_code | INDAPAMIDE tablets 2.5mg [GENUS] | drug | res9: diuretics_thiazide | 5252009 | 2020100 | Thiazides and related diuretics |
| 41517 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 5mg [TEVA] | drug | res9: diuretics_thiazide | 1663009 | 2020100 | Thiazides and related diuretics |
| 41556 | CPRD_product_code | CO-AMILOZIDE tablets 5mg+50mg [TEVA] | drug | res9: diuretics_thiazide | 1358010 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 41572 | CPRD_product_code | CO-TENIDONE tablets 100mg+25mg [TEVA] | drug | res9: diuretics_thiazide | 1655010 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 41861 | CPRD_product_code | TENSAID XL tablets 1.5mg [GEN (UK)] | drug | res9: diuretics_thiazide | 16593001 | 2020100 | Thiazides and related diuretics |
| 41885 | CPRD_product_code | ETHIBIDE XL prolonged release tablet 1.5mg [GENUS] | drug | res9: diuretics_thiazide | 16286001 | 2020100 | Thiazides and related diuretics |
| 42142 | CPRD_product_code | MODURETIC tablets [M S D] | drug | res9: diuretics_thiazide | 17614001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 42906 | CPRD_product_code | INDAPAMIDE tablets 2.5mg [NICHE] | drug | res9: diuretics_thiazide | 3986009 | 2020100 | Thiazides and related diuretics |
| 43184 | CPRD_product_code | MAPEMID XL prolonged release tablet 1.5mg [RATIOPHARM] | drug | res9: diuretics_thiazide | 17181001 | 2020100 | Thiazides and related diuretics |
| 4332 | CPRD_product_code | metolazone tablets 5mg | drug | res9: diuretics_thiazide | 4172001 | 2020100 | Thiazides and related diuretics |
| 43322 | CPRD_product_code | olmesartan medoxomil with hydrochlorothiazide tablets 40mg + 12.5mg | drug | res9: diuretics_thiazide | 17802001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 43516 | CPRD_product_code | INDAPAMIDE tablets 2.5mg [ACTAVIS] | drug | res9: diuretics_thiazide | 2252009 | 2020100 | Thiazides and related diuretics |
| 43915 | CPRD_product_code | OLMETEC PLUS tablets 40mg + 12.5mg [DAIIC-SANK] | drug | res9: diuretics_thiazide | 17803001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 44168 | CPRD_product_code | INDIPAM XL prolonged release tablet 1.5mg [ACTAVIS] | drug | res9: diuretics_thiazide | 17129001 | 2020100 | Thiazides and related diuretics |
| 4429 | CPRD_product_code | TRASIDREX tablets [GOLDSHIELD] | drug | res9: diuretics_thiazide | 968001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 4540 | CPRD_product_code | COZAAR-COMP tablets 50mg + 12.5mg [M S D] | drug | res9: diuretics_thiazide | 9922001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 45916 | CPRD_product_code | hydroflumethiazide with spironolactone tablets 50mg+50mg | drug | res9: diuretics_thiazide | 3797002 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 4605 | CPRD_product_code | MODUCREN tablets [M S D] | drug | res9: diuretics_thiazide | 1601001 | 02020100/02020300/02040000 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Beta-blocker |
| 46302 | CPRD_product_code | NEO-NACLEX tablets 2.5mg [MERCURY] | drug | res9: diuretics_thiazide | 18436001 | 2020100 | Thiazides and related diuretics |
| 46355 | CPRD_product_code | SEVIKAR HCT tablets 20mg + 5mg + 12.5mg [DAIIC-SANK] | drug | res9: diuretics_thiazide | 18543001 | 02020100/02060200/02050502 | Thiazides and related diuretics/Calcium channel blockers/Angiotensin-II antagonists |
| 46675 | CPRD_product_code | INDAPAMIDE SR tablets 1.5mg [HILLCROSS] | drug | res9: diuretics_thiazide | 7312009 | 2020100 | Thiazides and related diuretics |
| 46687 | CPRD_product_code | olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 20mg + 5mg + 12.5mg | drug | res9: diuretics_thiazide | 18538001 | 02020100/02060200/02050502 | Thiazides and related diuretics/Calcium channel blockers/Angiotensin-II antagonists |
| 46715 | CPRD_product_code | olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 40mg + 10mg + 12.5mg | drug | res9: diuretics_thiazide | 18540001 | 02020100/02060200/02050502 | Thiazides and related diuretics/Calcium channel blockers/Angiotensin-II antagonists |
| 46792 | CPRD_product_code | olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 40mg + 5mg + 12.5mg | drug | res9: diuretics_thiazide | 18539001 | 02020100/02060200/02050502 | Thiazides and related diuretics/Calcium channel blockers/Angiotensin-II antagonists |
| 46916 | CPRD_product_code | CO-AMILOZIDE tablets 5mg+50mg [HILLCROSS] | drug | res9: diuretics_thiazide | 320009 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 46952 | CPRD_product_code | CO-TENIDONE tablets 100mg+25mg [ACTAVIS] | drug | res9: diuretics_thiazide | 2230010 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 47467 | CPRD_product_code | olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 40mg + 5mg + 25mg | drug | res9: diuretics_thiazide | 18541001 | 02020100/02060200/02050502 | Thiazides and related diuretics/Calcium channel blockers/Angiotensin-II antagonists |
| 47573 | CPRD_product_code | SEVIKAR HCT tablets 40mg + 5mg + 12.5mg [DAIIC-SANK] | drug | res9: diuretics_thiazide | 18545001 | 02020100/02060200/02050502 | Thiazides and related diuretics/Calcium channel blockers/Angiotensin-II antagonists |
| 47616 | CPRD_product_code | SEVIKAR HCT tablets 40mg + 10mg + 12.5mg [DAIIC-SANK] | drug | res9: diuretics_thiazide | 18546001 | 02020100/02060200/02050502 | Thiazides and related diuretics/Calcium channel blockers/Angiotensin-II antagonists |
| 47727 | CPRD_product_code | SEVIKAR HCT tablets 40mg + 5mg + 25mg [DAIIC-SANK] | drug | res9: diuretics_thiazide | 18548001 | 02020100/02060200/02050502 | Thiazides and related diuretics/Calcium channel blockers/Angiotensin-II antagonists |
| 47804 | CPRD_product_code | CO-TRIAMTERZIDE tablets 50mg+25mg [HILLCROSS] | drug | res9: diuretics_thiazide | 7023009 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 47844 | CPRD_product_code | BENDROFLUMETHIAZIDE tablets 2.5mg [KENT] | drug | res9: diuretics_thiazide | 4546009 | 2020100 | Thiazides and related diuretics |
| 4796 | CPRD_product_code | INDERETIC capsules [ASTRAZENEC] | drug | res9: diuretics_thiazide | 1552001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 48039 | CPRD_product_code | LOSARTAN WITH HYDROCHLOROTHIAZIDE tablets 100mg + 12.5mg [TEVA] | drug | res9: diuretics_thiazide | 8153009 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 48079 | CPRD_product_code | INDAPAMIDE tablets 2.5mg [ZENTIVA] | drug | res9: diuretics_thiazide | 3023009 | 2020100 | Thiazides and related diuretics |
| 48098 | CPRD_product_code | perindopril erbumine with indapamide (roi) tablets 4mg + 1.25mg | drug | res9: diuretics_thiazide | 18402001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 48099 | CPRD_product_code | INDAPAMIDE tablets 2.5mg [HILLCROSS] | drug | res9: diuretics_thiazide | 3111009 | 2020100 | Thiazides and related diuretics |
| 48132 | CPRD_product_code | hydrochlorothiazide capsules | drug | res9: diuretics_thiazide | 15952001 | 2020100 | Thiazides and related diuretics |
| 4983 | CPRD_product_code | atenolol with amiloride and hydrochlorothiazide capsules | drug | res9: diuretics_thiazide | 5329001 | 02020100/02020300/02040000 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Beta-blocker |
| 5112 | CPRD_product_code | indapamide modified release tablet 1.5mg | drug | res9: diuretics_thiazide | 3870002 | 2020100 | Thiazides and related diuretics |
| 5189 | CPRD_product_code | enalapril with hydrochlorothiazide tablets 20mg + 12.5mg | drug | res9: diuretics_thiazide | 733001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 5330 | CPRD_product_code | CORGARETIC 40 tablets [SANOFI S] | drug | res9: diuretics_thiazide | 191001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 5416 | CPRD_product_code | co-triamterzide (triamterene and hydrochlorothiazide) tablets 50mg+25mg | drug | res9: diuretics_thiazide | 2268001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 542 | CPRD_product_code | hydrochlorothiazide tablets 25mg | drug | res9: diuretics_thiazide | 3787001 | 2020100 | Thiazides and related diuretics |
| 5721 | CPRD_product_code | co-tenidone (atenolol and chlortalidone) tablets 100mg+25mg | drug | res9: diuretics_thiazide | 6780002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 5727 | CPRD_product_code | cyclopenthiazide with amiloride tablets 250micrograms + 2.5mg | drug | res9: diuretics_thiazide | 6600001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 58 | CPRD_product_code | bendroflumethiazide tablets 5mg | drug | res9: diuretics_thiazide | 2782002 | 2020100 | Thiazides and related diuretics |
| 581 | CPRD_product_code | atenolol with chlortalidone tablets 50mg+12.5mg | drug | res9: diuretics_thiazide | 4978001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 6359 | CPRD_product_code | ZESTORETIC 10-tablets 10mg + 12.5mg [ASTRAZENEC] | drug | res9: diuretics_thiazide | 837002 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 6437 | CPRD_product_code | losartan with hydrochlorothiazide tablets 50mg + 12.5mg | drug | res9: diuretics_thiazide | 8759001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 6468 | CPRD_product_code | lisinopril with hydrochlorothiazide tablets 20mg + 12.5mg | drug | res9: diuretics_thiazide | 671001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 6786 | CPRD_product_code | lisinopril with hydrochlorothiazide tablets 10mg + 12.5mg | drug | res9: diuretics_thiazide | 671002 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 6794 | CPRD_product_code | perindopril erbumine with indapamide tablets 4mg + 1.25mg | drug | res9: diuretics_thiazide | 10694001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 6816 | CPRD_product_code | chlorothiazide oral suspension 250mg/5ml | drug | res9: diuretics_thiazide | 12043001 | 2020100 | Thiazides and related diuretics |
| 6877 | CPRD_product_code | CO-DIOVAN tablets 160mg + 12.5mg [NOVARTIS] | drug | res9: diuretics_thiazide | 12573001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 7066 | CPRD_product_code | metoprolol tartrate with hydrochlorothiazide tablets 100mg + 12.5mg | drug | res9: diuretics_thiazide | 5365002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 7136 | CPRD_product_code | DYTIDE capsules 50mg+25mg [GOLDSHIELD] | drug | res9: diuretics_thiazide | 292001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 7351 | CPRD_product_code | bendroflumethiazide oral suspension 2.5mg/5ml | drug | res9: diuretics_thiazide | 13871001 | 2020100 | Thiazides and related diuretics |
| 7543 | CPRD_product_code | KALTEN capsules [M&A PHARM] | drug | res9: diuretics_thiazide | 2050001 | 02020100/02020300/02040000 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Beta-blocker |
| 7618 | CPRD_product_code | xipamide tablets 20mg | drug | res9: diuretics_thiazide | 4383001 | 2020100 | Thiazides and related diuretics |
| 764 | CPRD_product_code | CO-DIOVAN tablets 80mg + 12.5mg [NOVARTIS] | drug | res9: diuretics_thiazide | 12787001 | 02020100/02050502 | Thiazides and related diuretics/Angiotensin-II antagonists |
| 7641 | CPRD_product_code | NATRILIX tablets 2.5mg [SERVIER] | drug | res9: diuretics_thiazide | 2704001 | 2020100 | Thiazides and related diuretics |
| 7698 | CPRD_product_code | APRINOX tablets 5mg [SOVEREIGN] | drug | res9: diuretics_thiazide | 56002 | 2020100 | Thiazides and related diuretics |
| 7740 | CPRD_product_code | triamterene with benzthiazide capsules 50mg+25mg | drug | res9: diuretics_thiazide | 4873001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 7961 | CPRD_product_code | spironolactone with hydroflumethiazide tablets 50mg+50mg | drug | res9: diuretics_thiazide | 4739002 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 8058 | CPRD_product_code | NORMETIC tablets [ABBOTT] | drug | res9: diuretics_thiazide | 3792001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 8147 | CPRD_product_code | LOPRESORETIC tablets [NOV/GEIGY] | drug | res9: diuretics_thiazide | 540001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 8189 | CPRD_product_code | SECADREX tablets [AVENTIS] | drug | res9: diuretics_thiazide | 848001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 8303 | CPRD_product_code | TENAVOID tablets [BURGESS] | drug | res9: diuretics_thiazide | 930001 | 02020100/04010200 | Thiazides and related diuretics/Anxiolytics |
| 8369 | CPRD_product_code | INDEREX capsules [ASTRAZENEC] | drug | res9: diuretics_thiazide | 1553001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 8464 | CPRD_product_code | meprobamate with bendroflumethiazide tablets | drug | res9: diuretics_thiazide | 4102001 | 02020100/04010200 | Thiazides and related diuretics/Anxiolytics |
| 8521 | CPRD_product_code | spironolactone with hydroflumethiazide tablets 25mg+25mg | drug | res9: diuretics_thiazide | 4739001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 8526 | CPRD_product_code | APRINOX tablets 2.5mg [SOVEREIGN] | drug | res9: diuretics_thiazide | 56001 | 2020100 | Thiazides and related diuretics |
| 8602 | CPRD_product_code | METENIX tablets 5mg [SANOFI/AVE] | drug | res9: diuretics_thiazide | 570001 | 2020100 | Thiazides and related diuretics |
| 8623 | CPRD_product_code | PRESTIM tablets [ICN] | drug | res9: diuretics_thiazide | 1183001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 8673 | CPRD_product_code | oxprenolol with cyclopenthiazide modified release tablet 160mg+0.25mg | drug | res9: diuretics_thiazide | 6789001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 8836 | CPRD_product_code | chlorothiazide tablets 500mg | drug | res9: diuretics_thiazide | 3303001 | 2020100 | Thiazides and related diuretics |
| 8891 | CPRD_product_code | HYGROTON -K tablets [NOV/GEIGY] | drug | res9: diuretics_thiazide | 452001 | 2020100 | Thiazides and related diuretics |
| 8897 | CPRD_product_code | TRIAM-CO tablets 50mg+25mg [IVAX] | drug | res9: diuretics_thiazide | 3794001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 8987 | CPRD_product_code | propranolol with bendroflumethiazide modified release capsules 160mg + 5mg | drug | res9: diuretics_thiazide | 5577002 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 9178 | CPRD_product_code | atenolol with bendroflumethiazide capsules 25mg + 1.25mg | drug | res9: diuretics_thiazide | 10709001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
| 9223 | CPRD_product_code | triamterene with hydrochlorothiazide tablets 50mg+25mg | drug | res9: diuretics_thiazide | 4871001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 923 | CPRD_product_code | co-amilozide (amiloride and hydrochlorothiazide) tablets 5mg+50mg | drug | res9: diuretics_thiazide | 5853002 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 924 | CPRD_product_code | co-amilozide (amiloride and hydrochlorothiazide) tablets 2.5mg+25mg | drug | res9: diuretics_thiazide | 5853001 | 02020100/02020300/02020400 | Thiazides and related diuretics/Potassium-sparing diuretics and aldosterone antagonists/Potassium-sp |
| 9764 | CPRD_product_code | CARACE 20 plus tablets [BMS] | drug | res9: diuretics_thiazide | 6251001 | 02020100/02050501 | Thiazides and related diuretics/ACE inhibitors |
| 9783 | CPRD_product_code | co-tenidone (atenolol and chlortalidone) tablets 50mg+12.5mg | drug | res9: diuretics_thiazide | 6780001 | 02020100/02040000 | Thiazides and related diuretics/Beta-blockers |
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ClinicalCodes is a project at the University of Manchester Institute of Population Health
The ClinicalCodes project is funded by the National Institute for Health Research (NIHR) School for Primary Care Research (SPCR)